primary effusion lymphoma

(redirected from serous lymphoma)

primary effusion lymphoma

a B cell lymphoma associated with human herpesvirus 8 infection, characterized by the occurrence of lymphomatous effusions in body cavities without the presence of a solid tumor.

primary effusion lymphoma

A very rare, high-grade human herpes virus 8- (HHV-8) associated large-cell lymphoma of body cavities with evidence of EBV infection, which primarily affects immunocompromised patients, especially those with HIV disease.

Clinical findings
Fever of unknown origin, shortness of breath, weakness, cough.
 
Risk factors
HCV, HIV, immunocompromise, elderly, asbestos exposure, solid organ transplantation.

Sites
Pleura, pericardium, or peritoneum, often with effusion.
 
Management
CHOP

Prognosis
Most patients die from the disease.

primary effusion lymphoma

A non-Hodgkin B-cell lymphoma that typically arises in body cavities such as the pleural, peritoneal, or pericardial spaces. It is caused by Kaposisarcoma herpesvirus (human herpes virus 8) and is usually found in patients with advanced immune suppression.
Synonym: body cavity lymphoma
See also: lymphoma