serotonin transporter


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serotonin transporter (SERT),

a protein, found for example in the terminal of a presynaptic neuron, which decreases the concentration of serotonin near the synapse by effecting its reuptake into the presynaptic neuron.
See also: presynaptic.
References in periodicals archive ?
Moderate level fetal alcohol exposure and serotonin transporter gene promoter polymorphism affect neonatal temperament and limbic-hypothalamic-pituitary-adrenal axis regulation in monkeys.
Serotonin transporter polymorphisms and adverse effects with fluoxetine treatment.
Drugs that affect serotonin transporters will interfere with platelet activation and, in combination with drugs that impair the coagulation cascade or with other aspects of platelet activation, bring a risk of increased bruising and abnormal bleeding.
Interactive effects of the serotonin transporter 5-HTTLPR polymorphism and stressful life events on college student drinking and drug use.
Serotonin transporter polymorphism mediates vulnerability to loss of incentive motivation following acute tryptophan depletion.
Obsessive compulsive disorder, response to serotonin reuptake inhibitors and the serotonin transporter gene.
Findings from earlier research have shown that proinflammatory cytokines can increase the density and activity of the serotonin transporter (SERT), a primary target for antidepressant therapy.
Sexual dichotomy of an interaction between early adversity and the serotonin transporter gene promoter variant in rhesus macaques.
Brain scans on 88 volunteers showed that a protein known as a serotonin transporter, which clears serotonin from the brain, is more active in autumn and winter.
There is essentially no mention by the author of genetic factors involved with certain mental illnesses (for example, the association of serotonin transporter genotypes in depression or cannabinoid receptor gene single nucleotide polymorphisms and ADHD).
Allelic variation in serotonin transporter function associated with the intensity dependence of the auditory evoked potential.
The next year, an article in the 18 July 2003 issue of Science showed that young people who go through emotionally stressful situations, such as losing a job or a romantic partner, are more prone to major depression if they inherit a variant form of the serotonin transporter gene, which participates in brain cell communication.