serotonergic drugs

serotonergic drugs (ser´ətōnur´jik), the prescription drugs used for weight loss that contain serotonin, a vasoconstrictor that acts as an appetite suppressant; examples are fenfluramine and dexfenfluramine (the
fen of Phen-fen), both of which have been removed from the U.S. market because of their links to heart valve disease, and fluoxetine, which has not been approved by the FDA for treatment of obesity.
References in periodicals archive ?
Serotonergic drugs in the treatment of depressive and anxiety disorders.
TABLE Drug treatment options for anxiety or depression in COPD (18, 19) Drug class Indications and Contraindications and dosage cautions Antianxiety GAD: 15-30 mg/d Hypersensitivity to drug -buspirone q 8-12h Use with caution in renal or hepatic impairment TCAs MDD: Acute Ml recovery -amitriptyline 100-200 mg at -nortriptyline night 25 mg q 6-8h Hypersensitivity to drug class Avoid abrupt withdrawal Use with caution in hepatic impairment, prolonged QT interval, and coadministration with serotonergic drugs (MAOI, linezolid, IV methylene blue) SSRI * MDD: Hypersensitivity to drug -sertraline 50-200 mg/d class Concomitant disulfram use Avoid abrupt withdrawal Use with caution in hepatic impairment SNRI * GAD: 37.
The development of a potentially life-threatening serotonin syndrome has been reported with SSRIs, including paroxetine, alone but particularly with concomitant use of serotonergic drugs (including triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, tryptophan, buspirone, and St.
The statements advise that linezolid or methylene blue should "generally not be given" to patients on serotonergic drugs.
The effects of serotonergic drugs on the locomotor pattern and on cutaneous reflexes of the adult chronic spinal cat.
For example, the combination of serotonergic drugs with MDMA may potentially place users at risk for serotonin syndrome (Oesterheld et al.
Any antidepressant that increases serotonin may precipitate a rare but serious adverse event known as serotonin syndrome, which can be associated with monotherapy or combinations of serotonergic drugs.
Dextromethorphan can cause serotonin syndrome when taken with serotonergic drugs such as amphetamines, cocaine, monoamine oxidase inhibitors, or selective serotonin reuptake inhibitors.
Triptans, which are 5-hydroxytryptamine receptor agonists used to treat migraine; and SSRIs and SNRIs, used to treat depression and other mood disorders, are serotonergic drugs.
The pharmacology of impulsive behaviour in rats VI: the effects of ethanol and selective serotonergic drugs on response choice with varying delays of reinforcement.
It would seem essential that the large number of novel serotonergic drugs currently under investigation be examined for treatment in Alzheimer-type dementia," Cross says.
If concomitant use of PRISTIQ with other serotonergic drugs is clinically warranted, patients should be made aware of a potential increased risk for serotonin syndrome, particularly during treatment initiation and dose increase.