seronegative


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Related to seronegative: Seronegative spondyloarthritis

seronegative

 [se″ro-neg´ah-tiv]
showing negative results on serologic examination; showing a low level of antibody.

se·ro·neg·a·tive

(sē'rō-neg'ă-tiv),
Lacking an antibody of a specific type in serum; used to mean absence of previous infection with a specific agent (for example, rubella virus), disappearance of antibodies after treatment of a disease (for example, syphilis), or absence of antibody usually found in a given syndrome (for example, rheumatoid arthritis without rheumatoid factor).

seronegative

/se·ro·neg·a·tive/ (-neg´ah-tiv) showing negative results on serological examination; showing a lack of antibody.

seronegative

(sîr′ō-nĕg′ə-tĭv)
adj.
Indicating a negative reaction to a serological blood test, especially one testing for the presence of antibodies.

seronegative

[-neg′ətiv]
Etymology: L, serum, whey, negare, to deny
a serological test with negative results.

seronegative

Immunology The lack of antibodies or other immune markers in serum that would indicate exposure to a particular organism or antigen; in an immunocompetent person, exposure to an antigen results in a seroconversion and the subject is said to then be seropositive. Cf Seropositive.

se·ro·neg·a·tive

(sēr'ō-neg'ă-tiv)
Lacking an antibody of a specific type in serum; denoting absence of prior infection with a specific agent, disappearance of antibodies after treatment of a disease, or absence of antibody usually found in a given syndrome.

se·ro·neg·a·tive

(sēr'ō-neg'ă-tiv)
Lacking an antibody of a specific type in serum.

seronegative (sir´ōneg´ətiv),

n serologic evidence of the lack of an antibody of a specific type in the serum; diagnostically useful in ruling out Lyme disease, syphilis, human immunodeficiency virus (HIV), serum hepatitis B, and many other viral diseases.

seronegative

showing a negative serum reaction; i.e. an animal with no detectable serum antibodies to a specified microorganism.
References in periodicals archive ?
Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome: a review of the literature and a report of three cases.
The frequency of IgA antibody in urine was most common in the seronegative partners of HIV-1-positive subjects (partners), and STD and MSP cohorts.
An international, 8-month study of nearly 1,500 couples (in which one partner had genital herpes and the other was seronegative and had no history of genital herpes) showed that only 0.
In cases of HCV this is of limited relevance because antibody testing has been introduced, although some HCV antibody seronegative infections will certainly exist.
Although KDIGO([R]), KDOQI, and CDC recommendations each specify screening seronegative patients every 6-12 months for the surveillance of HCV infection in HD facilities, the clinical utility of recommended tests has not been examined in large populations.
In addition, HIV in patients who are seronegative is extremely rare, particularly in the setting of current screening ELISAs (2).
HIV-positive women were more likely to develop malaria attacks during pregnancy than seronegative women.
The reasons are not clearly understood, but we have a handful of people who have been to our clinic over the last 20 years who, despite having culture-positive genital HSV-1 infection, are still seronegative on the Western blot for HSV-1," Dr.
HIV-seropositive participants were less likely than their seronegative counterparts to accept referral, "possibly because of being overwhelmed by many clinical appointments, needing to focus predominantly on HIV infection or the prospect of additional complicated therapies, or difficulty establishing a new provider relationship," said Dr.
Only 3% of the seronegative valacyclovir recipients and none of the seropositive valacyclovir recipients developed CMV, reports David Lowance, MD of Piedmont Hospital in Atlanta, Ga.
PCR [Polymerase Chain Reaction] negative and seronegative for all 4 vaccine HPV types) to all 4 vaccine HPV types at enrollment.
Seropositive and seronegative hunters did not differ significantly with respect to sex, age, and total years of hunting.