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seroconversion

   Also found in: Dictionary/thesaurus, Wikipedia 0.01 sec.
seroconversion /se·ro·con·ver·sion/ (-con-ver´zhun) the change of a seronegative test from negative to positive, indicating the development of antibodies in response to immunization or infection.
se·ro·con·ver·sion (sîr-kn-vûrzhn, -shn)
n.
Development of antibodies in blood serum as a result of infection or immunization.

Seroconversion
The change from HIV-negative to HIV-positive status during blood testing. Persons who are HIV-positive are called seroconverters.
Mentioned in: AIDS Tests

seroconversion
[- kənvur′zhən]
Etymology: L, serum, whey, conversio, turned about
a change in serologic test results from negative to positive as antibodies develop in reaction to an infection or vaccine.

seroconversion [se″ro-kon-ver´zhun]
the change of a serologic test from negative to positive, indicating the development of antibodies in response to infection or immunization.

seroconversion (sirˈ·ō·kn·verˑ·zhn),
n change of serologic test results from negative to positive because of antibodies that develop in reaction to a vaccine or infection.

seroconversion (sir´ōknvur´zhn),
n a blood test in which the amount of time required for the blood to change from seronegative to seropositive is indicative of specific diseases.

seroconversion
the development of antibodies to an infectious organism in response to natural infection or to the administration of a vaccine.

seroconversion
Immunology The development of antibodies detectable in the serum, after exposure to a particular organism or antigen, in a person who was previously immunologically 'naive' for–ie, previously unexposed to a particular antigen; seroconversion may indicate current infection–and transmissibility of a pathogen–eg, HIV-1–seroconversion to p24 and/or p41 antibody production or HBV–seroconversion to surface antibody-HBsAb or e antibody–HBeAb production. See Seropositive. Cf Seronegative.


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This phase may last for several weeks to years and if successful, HBeAg seroconversion will occur with the development of sustained HBe-antibody titres.
There are several possible explanations for the patient's HIV seroconversion failure.
To compare mortality rates, the investigators used a large data set comprising 21 separate cohorts of HIV-infected subjects whose dates of seroconversion (development of serum antibodies as a result of infection) had been pinned down relatively precisely These cohorts included 16,534 subjects who were followed for up to 23 years in 10 European countries, Australia, and Canada.
 
 
 
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