serious risk

serious risk

EBM
A term of art used in a clinical trial for the potential occurrence of a serious adverse experience.
References in classic literature ?
Our physicians have discovered that the small and tender sides of an infant Polygon of the higher class can be fractured, and his whole frame re-set, with such exactness that a Polygon of two or three hundred sides sometimes -- by no means always, for the process is attended with serious risk -- but sometimes overleaps two or three hundred generations, and as it were doubles at a stroke, the number of his progenitors and the nobility of his descent.
If, on the other hand, they chose to-night to sit far back inside the room, then the chances were that I should hear little or nothing--and in that case, I must run the far more serious risk of trying to outwit them downstairs.
Half of the 60 largest economies face a serious risk of water shortages in the future unless climate policy changes.
You a serious risk of sexual harm women children SHERIFF He added: "I view you as a serious risk to women and you pose a serious risk of sexual harm to both women and children.
Prop 46 is a serious risk to my patients -- and California C that's why I'm voting no.
It revealed: "Immediate serious risk identified was in relation to observations of non-compliance with hand hygiene practice in the Emergency Department.
Of the 2278 notifications, 1938 notifications concerned products which posed a serious risk to consumers, while the others referred to moderate risk or information only.
In the approval letter for Qsymia, the FDA stated that because there have been signals of a serious risk of major adverse cardiovascular events with some medications developed for treating obesity, and available data "have not definitively excluded the potential for this serious risk" with the phentermine-topiramate combination, only a clinical trial will be "sufficient to assess a signal of a serious risk of major adverse cardiovascular events with anti-obesity medications, including Qsymia.
The gas supply to the premises was immediately cut off to remove a serious risk.
RESIDENTS of a proposed housing estate next to a former landfill site are not at serious risk of gas leaks, it has been claimed.
IT is simply not acceptable that Britain cannot deport a radical Muslim cleric who "poses a serious risk to our national security", the Home Secretary said yesterday.
ISLAMABAD, February 14, 2011 (Balochistan Times): Commuters travelling between Rawalpindi and Islamabad and on intra-city mini vans have demanded a ban on unauthorised us of CNG cylinders in public service vehicles as they pose a serious risk to life and property.

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