sequestrant


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sequestrant

 [se-kwes´trant]
a sequestering agent, such as cholestyramine resin (which binds bile acids in the intestine and prevents their absorption).

sequestrant

/se·ques·trant/ (se-kwes´trant) a sequestering agent, as, for example, cholestyramine resin, which binds bile acids in the intestine, thus preventing their absorption.

sequestrant

A food additive which improves the quality and/or stability of a food product—e.g., by binding polyvalent metallic ions (e.g., copper, iron, nickel), preventing discolouration and inhibiting reactions that result in rancidity.

sequestrant

a sequestering agent, as, for example, cholestyramine resin which binds bile acids in the intestine, thus preventing their absorption.
References in periodicals archive ?
Reductions in sitosterol and campesterol were consistent between patients taking ZETIA concomitantly with bile acid sequestrants (n=8) and patients not on concomitant bile acid sequestrant therapy (n=21).
The statin/gemfibrozil combination has the highest risk of myopathy, whereas statin/ ezetimibe or statin/bile acid sequestrant have the least increased risk (SOR: B).
Bile acid sequestrants: Because co-administration of bile acid sequestrants may reduce the bioavailability of acidic medicinal products such as nicotinic acid, it is recommended that Tredaptive be administered > 1 hour before or > 4 hours after administration of a bile acid sequestrant.
Three subsequent clinical trials reported in 2008 evaluated the glucose and lipid-lowering effects of colesevelam HC1, which is a specifically engineered bile acid sequestrant developed in the 1990s as a high-affinity, high-capacity bile acid-binding molecule.
Dosing of ZETIA should occur either greater than or equal to 2 hours before or greater than or equal to 4 hours after administration of a bile acid sequestrant (see PRECAUTIONS, Drug Interactions).
MEVACOR is effective alone or when used concomitantly with bile-acid sequestrants.
The bile acid sequestrant colesevelam HCl, sold under the name WelChol, has been approved in the United States for LDL cholesterol lowering since 2000.
Small reductions from baseline in basal plasma testosterone in men were observed in clinical studies with simvastatin, an effect also observed with other inhibitors of HMG-CoA reductase and the bile acid sequestrant cholestyramine.
Coadministration with Bile Acid Sequestrants Dosing of VYTORIN should occur either (greater than=)2 hours before or (greater than=)4 hours after administration of a bile acid sequestrant (see PRECAUTIONS, Drug Interactions).
Combinations of a statin and niacin are the most popular, but combinations of a statin and a fibrate or a statin and a bile acid sequestrant are also used.
Colesevelam hydrochloride: Usefulness of a specifically engineered bile acid sequestrant for lowering LDL-cholesterol.
Fish scales can be seen in histologically processed gallbladder calculi (A), dystrophic calcifications (B), unspecified luminal material (favor food; C), and occasionally in large bile acid sequestrant fragments (see Figures 4, C and F, and 5), suggesting that fish scales are a histologic artifact of knife-cutting.