As we continue to collect data in the prospective cohort, we hope to refine our understanding of which candidates are most likely to benefit from sequential therapy
, and to use this knowledge to extend patients' lives.
The oestrogen-progestin sequential therapy
supports female secondary sexual characteristics.
Third-line sorafenib after sequential therapy
with sunitinib and mtor inhibitors in metastatic renal cell carcinoma.
Future studies should be longer in duration to accumulate more evidence regarding predictors of long-term fracture incidence after bisphosphonate withdrawal and to identify an outcomes-based bisphosphonate washout period for trials of sequential therapy
consists of a PPI with amoxicillin for the first 5 days and then clarithromycin with metronidazole and a PPI for the next 5 days.
11] Thus eradication is not achieved in at least 1/5 patients, prompting research on sequential therapy
NEW ORLEANS -- For eradication of Helicobacter pylori infection, a 14-day hybrid therapy that combines sequential and concomitant drug treatments improved the eradication rate, compared with 14-day standard sequential therapy
, investigators reported.
In addition, the availability of sequential therapy
and predictive testing has created new challenges in determining an actual overall or progression-free survival benefit for any new agents or regimens.
The Spanish Head and Neck Cancer Cooperative Group (TTCC) announced today that Induction Chemotherapy (IC) delivered prior to standard ChemoRadiotherapy (CRT), a treatment paradigm defined as sequential therapy
, compared to upfront CRT alone, significantly prolonged Time-to-Treatment Failure (TTF) for patients with unresectable Locally Advanced Head and Neck Cancer (LAHNC).
Abstract #114: A Randomized Phase II, Open-Label Study of Sipuleucel-T with Concurrent or Sequential Abiraterone Acetate (AA) in Metastatic Castrate-Resistant Prostate Cancer (mCRPC): A Phase II study evaluating concurrent or sequential therapy
with AA plus prednisone (P) in men with metastatic castrate resistant prostate cancer demonstrated no significant differences in median cumulative CD54 upregulation (31.
Recurrent glioblastoma patients in the Phase 1b "TARGET 1" trial ( T herapeutic A denovirus for R ecurrent G lioblastoma E ffec T trial) are being randomized to receive sequential therapy
of DNX-2401 plus or minus interferon gamma.
The optimal timing and duration of aromatase inhibitor (AI) treatment are not yet resolved, but it appears to reduce the risk of recurrence when taken at some time during adjuvant therapy--either alone as monotherapy, as sequential therapy
before tamoxifen therapy commences or after 2-3 years of tamoxifen treatment, or as extended therapy after 5 years of tamoxifen is completed, said Dr.