4-Sep

(redirected from septin 4)

4-Sep

A gene on chromosome 17q22 that encodes septin 4, a member of the septin family of nucleotide-binding proteins, which regulate cytoskeletal organisation. SEPT4 is highly expressed in brain and heart; its disruption alters cytokinesis.
References in periodicals archive ?
The Rockefeller University laboratory of Hermann Steller created mice that lack the gene septin 4.
Microscopic examination revealed that these sperm are missing the annulus, suggesting that this structure may be made of septin 4 protein, the production of which is controlled by the septin 4 gene.
Studying sperm from mice lacking septin 4, which no longer have an annulus, will allow us to finally ask if the annulus truly acts as a turnstile," says Hunnicutt.