sepsis syndrome

A constellation of signs, Sx, and systemic responses caused by a wide range of microorganisms that may eventuate into septic shock; SS is a systemic response to infection

Sepsis syndrome, defining parameters

• Temperature Hypothermia < 35ºC–96ºF or hyperthermia > 39ºC–101ºF

• Tachycardia > 90 beats/minute

• Tachypnea > 20 breaths/minute

• Site of infection Clinically evident focus of infection or positive blood cultures

• Organ dysfunction 1+ end organs with either dysfunction or inadequate perfusion or cerebral dysfunction

• Metabolic derangement Hypoxia–PaO₂ < 75 mm Hg, ↑ plasma lactate/unexplained metabolic acidosis

• Fluid imbalance Oliguria–< 30 mL/hr

• WBC counts < 2.0 x 10⁹/L; > 12.0 x 10⁹/L–US: < 2000/mm³; > 12 000/mm³

Note: The confusing semantics of the terms sepsis, sepsis/septic syndrome, and septic shock are unlikely to be resolved in the forseeable future; the terms sepsis and septic syndrome are essentially interchangeable and would in part overlap with septicemia–the early components of a pernicious infectious cascade that has spilled into the circulation; the term septic shock is used when the process becomes virtually irreversible

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arrhythmia mapping Beri-beri beta-hemolytic streptococci cardiac output hypersensitivity Increased Rate of Breathing leukocytosis midrange pathologic septic shock septic syndrome septicemia syndrome temperament	Epidemiology of sepsis syndrome in 8 academic medical centers: Academic Medical Center Consortium Sepsis Project Working Group. Recognizing and managing severe sepsis: a common and deadly threat by McCollam, Jill Shwed / Southern Medical Journal Sepsis syndrome and failure to institute treatment with antifungal drugs (the latter occurred mainly in preterminal hematology patients) were independent predictors of death. Active surveillance for candidemia, Australia by Sorrell, Tania / Emerging Infectious Diseases Among the CLAL studies, 10 were limited to patients meeting the criteria of sepsis syndrome (SS),[64] and this subgroup was compared with the other CLAL studies (non-SS studies). Concordance of Endotoxemia With Gram-Negative Bacteremia by Hurley, James C. / Archives of Pathology & Laboratory Medicine	sentinel node sentinel node biopsy sentinel pile Sentinel Surveillance sentinel tag sentry dog Seoul Virus Sep SEPA SEPA/alprostadil separating spring separating wire separation separation agent separation anxiety separation anxiety disorder separation factor separation from group separation phase separation-individuation separator Sephadex Sepracoat seps- sepsis sepsis syndrome sepsis, oral sept- septa septal septal cartilage septal defect Septal defects Septal hematoma septan Septata intestinalis septate septate uterus septectomy September Club septi- septic septic abortion septic arthritis septic fever septic infarct septic phlebitis septic shock septic sore throat septic syndrome septic-	SEPRATS SEPRE SEPREDI SEPRELAD SEPREM SEPRI SEPRM SEPROM SEPRONA SEPRORS SEPROS SEPROSE SEPRT SEPS SEPS SEPS SEPS SEPS seps- SEPSA SEPSCoR sepses sepses sepses SEPSI Sepsidae Sepsin sepsis sepsis sepsis sepsis syndrome Sepsis syndrome, defining parameters sepsis, oral Sepsis, Posttraumatic Sepsis-related Organ Failure Assessment SEPSS sept sept sept sept Sept 1 Sept 10 Sept 11 Sept 11 Sept 12 Sept 13 Sept 14 Sept 15 Sept 16 Sept 17 Sept 17 Sept 18 Sept 19 Sept 2 Sept 20 Sept 21 Sept 22 Sept 23 Sept 24 Sept 25

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References in periodicals archive

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arrhythmia mapping
Beri-beri
beta-hemolytic streptococci
cardiac output
hypersensitivity
Increased Rate of Breathing
leukocytosis
midrange
pathologic
septic shock
septic syndrome
septicemia
syndrome
temperament

Epidemiology of sepsis syndrome in 8 academic medical centers: Academic Medical Center Consortium Sepsis Project Working Group.

Recognizing and managing severe sepsis: a common and deadly threat by McCollam, Jill Shwed / Southern Medical Journal

Sepsis syndrome and failure to institute treatment with antifungal drugs (the latter occurred mainly in preterminal hematology patients) were independent predictors of death.

Active surveillance for candidemia, Australia by Sorrell, Tania / Emerging Infectious Diseases

Among the CLAL studies, 10 were limited to patients meeting the criteria of sepsis syndrome (SS),[64] and this subgroup was compared with the other CLAL studies (non-SS studies).

Concordance of Endotoxemia With Gram-Negative Bacteremia by Hurley, James C. / Archives of Pathology & Laboratory Medicine