sentinel lymph node


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sentinel lymph node

the first lymph node to receive lymphatic drainage from a malignant tumor; the sentinel nodes are identified as the first to take on a radionuclide or dye injected into the tumor; increasingly used in operations for melanoma and breast cancer; if the sentinel nodes are free of metastasis, more distal nodes are usually also free.
See also: signal lymph node.

sen·ti·nel lymph node

(sen'ti-nĕl limf nōd)
The first lymph node to receive lymphatic drainage from a malignant tumor; the sentinel node is identified as the first to take up a radionuclide or dye injected into the tumor; increasingly used in operations for melanoma and breast cancer; if the sentinel node is free of metastasis, more distal nodes are also free.
See also: signal lymph node

Sentinel lymph node

The first lymph node to receive lymph fluid from a tumor. If the sentinel node is cancer-free, then it is likely that the cancerous cells have not metastasized.
Mentioned in: Vulvar Cancer
References in periodicals archive ?
Sentinel lymph node surgery after neoadjuvant chemotherapy in patients with node-positive breast cancer: The ACOSOG Z1071 (Alliance) Clinical Trial.
The importance of applying a sentinel lymph node mapping algorithm in endometrial cancer staging: beyond removal of blue nodes.
Diagnostic Validity Tests calculating sensitivity, specificity, false negative, positive predictive value, negative predictive value and accuracy of the sentinel lymph node biopsy were done after final histopathology report was available in comparison with rest of the axillary lymph nodal status to assess the efficacy of sentinel lymph node biopsy in detecting axillary metastasis.
14) Sentinel lymph nodes will be covered in Part Two of this article.
A randomized clinical trial on sentinel lymph node biopsy versus axillary lymph node dissection in breast cancer: results of the Sentinella/GIVOM trial.
Sentinel lymph node biopsy in patients with thick (=4 mm) melanoma: a single-centre experience.
Evaluation of intraoperative scrape cytology for sentinel lymph node biopsy in patients with breast cancer.
A positive sentinel lymph node biopsy indicates the tumor has metastasized and can be used to determine the stage of the cancer.
Objectives: To assess the diagnostic value of sentinel lymph node localisation using pre-operative lymphoscintigraphy and intra-operative gamma probe radio localisation in Pakistani patients suffering from early stage squamous cell carcinoma of the oral cavity.
The sentinel lymph node (SLN) is the first lymph node (LN) through which cancer cells are detected from the primary site.
This intra-operative imaging technology contributes to quality assurance and provides evidence for complete sentinel lymph node and tumor resection during the surgery.
Summary: The aim of the present study was to radiolabel and bioevaluate the dextran cysteamine mannose (MW=22 kDa) for sentinel lymph node detection.