He said media, civil society and religious scholars should keep sensitizing
the public about preventive measures against dengue.
However, it must be acknowledged that, although collectively the methods listed above are a source of valuable information about the properties of novel proteins and allow identification of proteins that are likely to cause sensitization on the basis of their structural similarity to known allergens, they do not provide a definitive assessment of inherent sensitizing potential.
Regardless of a detailed understanding of the biologic and/or structural properties of proteins that govern their differential sensitizing activity, attempts to identify inherent allergenic hazard in the context of a safety assessment are predicated on the basis of being able to model such differences experimentally.
1994)], 2% OVA, or 10% potato protein extract [PPE; containing proteins that are considered not to possess significant sensitizing potential (Dearman et al.
It is our view that the results of experiments in which inherent sensitizing potential is measured must be incorporated into an holistic safety assessment that also includes consideration of the sites and levels of expression of the protein of interest in modified crops plants and the likely exposure of consumers to foods or food products derived from such crops.
To study the sensitizing potential of new proteins, animal models need to satisfy several important criteria (Penninks and Knippels 2001; Taylor and Lehrer 1996), which are not easy to achieve in one single model.
Between crude raw or roasted peanut extracts, no clear differences were observed in the sensitizing potency as measured by the Th2-mediated IgG2a production at dose levels ranging from 0.
In the second study, the oral sensitizing potential decreased in the order Ara h1 > Pen a1 > Sol t1, with no sensitization to beef tropomyosin in both studies.
Barrentine, 54, joined Kodak in 1972 and has held a broad range of management positions in manufacturing, including manager of Operations for Color Film Sensitizing
, divisional flow manager for Advanced Media Manufacturing, operations manager of Color Paper Manicuring, and unit manager for Color Film Sensitizing
The receipt of this patent enhances GenStar's unique approach to treating prostate cancer via multiple modes of action that includes sensitizing
tumors to the effects of standard radiation by gene therapy," said Robert E.
When our initial investments are complete next year, we will have capacity sufficient to meet domestic demand for the next five years and will be sensitizing
the majority of the consumer products and many of the Health Imaging and Kodak Professional products we sell in China," said David Swift, chairman and president of Kodak's Greater Asia Region.
Antibodies to the allergen are produced, which bind to mast cells, sensitizing
the body to future exposure to the allergen.