semialdehyde

sem·i·al·de·hyde

(sem'ē-al'dĕ-hīd),
The monoaldehyde of a dicarboxylic acid, so called because half the COOH groups of the original acid are reduced to the aldehyde, whereas the other half are unchanged, for example, glutamic acid γ-semialdehyde, OHC-CH2CH2CH(NH3)+-COO-. Many semialdehydes are intermediates in the biosynthesis and metabolic degradation of amino acid, for example, l-proline, l-lysine, l-glutamate.
References in periodicals archive ?
Xyrem is contraindicated in combination with sedative hypnotics or alcohol and in patients with succinic semialdehyde dehydrogenase deficiency.
A ketogenic diet rescues the murine succinic semialdehyde dehydrogenase deficient phenotype.
Emma was diagnosed with the condition Succinic semialdehyde dehydrogenase deficiency at just eight months old in 2011.
Catechol is oxidized to 2-hydroxymuconic semialdehyde.
In the gastrodin-treated group, both succinic semialdehyde dehydrogenase (SSADH) and succinic semialdehyde reductase (SSAR) immunoreactivities in the hippocampus was also decreased significantly, which stood in contrast to the nontreated group, in which strong SSADH and SSAR immunoreactivities were detected.
Jake, who attends Rowan Park special school in Litherland, has suffered with his condition, succinic semialdehyde dehydrogenase deficiency, since he was a toddler.
The scientists discovered that Synechococcus indeed had genes that coded for one important alternative enzyme, succinic semialdehyde dehydrogenase, and that adjacent to the gene for this enzyme was a misidentified gene that subsequently was shown to encode a novel enzyme, 2-oxo-glutarate decarboxylase.
protein carbonyis and derivates like 2-amino-adipic semialdehyde, [gamma]-glutamyl-semialdehyde as well as cross-linked proteins like membrane bound haemoglobin).
Activity of catechol 1,2 dioxygenase and catechol 2,3 dioxygenase were done by detecting the formation of key intermediates of degradation pathway such as cis,cis muconic acid and 2-hydroxy muconic semialdehyde at 260 and 375 nm at 25[degrees]C.
Mary Jane's son, Bart (29), has succinic semialdehyde dehydrogenase deficiency and lives in his own apartment supported by 24-hour caregivers.
Selon plusieurs auteurs, ce phenomene peut s'expliquer par l'accumulation du semialdehyde 2-hydroxymuconique, lequel est un intermediaire dans le clivage meta du phenol qui inhibe la consommation de celui-ci (Leonard et al.