self-reactive


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self-reactive

(sĕlf′rē-ăk′tĭv)
adj.
Immunologically reactive to itself. Used of a cell or antibody.
References in periodicals archive ?
SHP-1 plays an important role in maintaining tolerance of self-reactive B cells, because conditional B cell-specific deletion of SHP-1 induces activation of self-reactive B cells and production of autoantibodies.
Scientists believe that's because these autoimmune patients produce self-reactive antibodies that recognize and neutralize HIV-1.
2006) found that people's expected status outcomes, monetary outcomes, novelty outcomes, social outcomes, and self-reactive outcomes are all positively related to multiplayer online gaming usage.
it allows for the presentation of a greater number of antigenic peptides, which has been postulated to allow thymic selection of self-reactive T cells that are activated in the periphery when encountering self-antigens.
becomes self-reactive under conditions of shock or increase in pressure or temperature; e.
Several investigators now propose that one of the body's initial responses to infection, the production of a compound called interleukin-12, may also awaken self-reactive immune cells.
The National Geographic article highlights its ability to suppress self-reactive inflammatory processes in autoimmune diseases such as multiple sclerosis and lupus without shutting down the entire immune system.
Supply test for determination of glucose and ketone testing strips, bound for dependent health centers in the Regional Health Management of Castilla y LeEn, and made available to the petitioner center measuring equipment compatible with the test strip (one meter every 2 team 500 for self-reactive patients and strip each other Commercial 3000).
We've shown that by blocking PI3Kgamma, we can reduce the activation of self-reactive immune cells, reduce the release of inflammation-inducing molecules from immune cells, and also result in a dramatic reduction in the movement of immune cells into the central nervous system.
In several autoimmune diseases, including multiple sclerosis and rheumatoid arthritis, self-reactive T cells escaped immune checkpoints.
Tovaxin(TM) targets the specific self-reactive T-cell receptor with the goal of avoiding the deleterious side effects of current MS therapies.
Tovaxin(TM) targets the specific self-reactive T-cell receptor in a targeted manner with the goal of avoiding the deleterious side effects of current MS therapies.