selenium intoxication

selenium intoxication

Toxicology A rare condition caused by acute or chronic selenium excess; SI is linked to occupational exposure to selenium in manufacture of photocopiers, red lights, photoelectric cells Clinical Pallor, garlicky odor, metallic taste, GI complaints, nasal irritation, conjuctivitis, dermatitis, reversible balding, drowsiness, chest constriction, intestinal distress, weakness and slower mentation Ref range Negative; general population, 3–52 µg/g creatinine. Cf Selenium deficiency.
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To avoid selenium intoxication, Underwood (1981) proposed the use of antagonistic elements, aiming to reduce their accumulation in tissue as well as its absorption in the digestive tract.
Yang G, Wang S, Zhou R, Sun S (1983) Endemic selenium intoxication of humans in China.