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selenium deficiency

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selenium deficiency
Cardiology An absence of selenium in the diet, with ↑ binding of hepatic nucleoproteins to DNA regulatory sequences, and activation of transcription in response to oxidative stress; SD has been implicated in colon polyp formation, endemic cardomyopathy, Keshan disease–attributed to a defect in glutathione peroxidase activity, without which there is ↑ platelet aggregation due to impaired free radical salvage or in the catalytic function of type I deiodinizing thyroxine-activating enzyme. See Keshan disease.


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Selenium deficiency can cause a particular type of arthritis called Kashin Bek disease, but it is more common where the soil is deficient in selenium, though sufferers of RA have less in their blood than others.
According to a research in Scotland University, scientists have identified around 40 diseases related to selenium deficiency.
The researchers point out that this raises a potentially important public health question: has selenium deficiency been overlooked as a cause of anemia among older adults?
 
 
 
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