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selenium deficiency |
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selenium deficiency
Cardiology An absence of selenium in the diet, with ↑ binding of hepatic nucleoproteins to DNA regulatory sequences, and activation of transcription in response to oxidative stress; SD has been implicated in colon
polyp formation, endemic cardomyopathy, Keshan disease–attributed to a defect in glutathione peroxidase activity, without which there is ↑ platelet aggregation due to impaired free radical salvage or in the catalytic function of type I
deiodinizing thyroxine-activating enzyme. See Keshan disease. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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