selective norepinephrine reuptake inhibitor

selective norepinephrine reuptake inhibitor

a class of chemical compounds that selectively, to varying degrees, inhibit the reuptake of norepinephrine by the presynaptic neurons and are posited to exert their antidepressant effect by this mechanism.

se·lec·tive nor·ep·i·neph·rine re·up·take in·hib·i·tor

(SNRI) (sĕ-lektiv nōr-epi-nefrin rē-ŭptāk in-hibi-tŏr)
A class of chemical compounds that selectively, to varying degrees, inhibit reuptake of norepinephrine by the presynaptic neurons; thought to exert their antidepressant effect by this mechanism.

se·lec·tive nor·ep·i·neph·rine re·up·take in·hib·i·tor

(sĕ-lektiv nōr-epi-nefrin rē-ŭptāk in-hibi-tŏr)
Class of chemical compounds that selectively, to varying degrees, inhibit reuptake of norepinephrine.
References in periodicals archive ?
In 2010, Lilly launched the Phase III program for edivoxetine - a potent and highly selective norepinephrine reuptake inhibitor - to assess the benefits and risks of edivoxetine as an add-on therapy in patients with MDD.
Major finding: Patients with depression who did not respond adequately to a course of selective serotonin reuptake inhibitor or selective norepinephrine reuptake inhibitor therapy and who were then switched to double-blind treatment with the novel antidepressant vortioxetine had a 55% remission rate after 8 weeks of therapy.
Between 5% and 14% of patients on a selective serotonin reuptake inhibitor (SSRI) or a selective norepinephrine reuptake inhibitor (SNRI) develop drug-induced excessive sweating.
Reboxetine is a selective norepinephrine reuptake inhibitor used in the United Kingdom.
Stimulants such as methylphenidate, amphetamines, and pemoline, as well as the selective norepinephrine reuptake inhibitor atomoxetine, are known to raise heart rate and to increase systolic blood pressure by approximately 2-5 mm Hg and diastolic blood pressure by 1-3 mm Hg.
Strattera, a selective norepinephrine reuptake inhibitor, works differently than other FDA-approved treatments for the disorder, all of which are stimulants.
A selective norepinephrine reuptake inhibitor, Strattera represents the first new class of ADHD medications in the 50 years since stimulant medications first began being used.
Physicians and patients may be alarmed by recent changes to the product labels of the selective serotonin reuptake inhibitors and the selective norepinephrine reuptake inhibitor venlafaxine with respect to their use during pregnancy.
In late July, the FDA issued an approvable letter regarding reboxetine, a selective norepinephrine reuptake inhibitor, for the treatment of depression.
Strattera, a selective norepinephrine reuptake inhibitor, works differently than any older FDA-approved treatments for the disorder, all of which are stimulants.
A few studies have shown that augmenting lithium with an SSRI or a selective norepinephrine reuptake inhibitor may help improve bipolar depression.
Strattera is a selective norepinephrine reuptake inhibitor marketed by Eli Lilly and Company (NYSE:LLY) for treatment of ADHD in children, adolescents and adults.

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