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selective estrogen receptor modulator |
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Selective estrogen receptor modulator A hormonal preparation that offers the beneficial effects of hormone replacement therapy without the increased risk of breast and uterine cancer associated with HRT. Mentioned in: Osteoporosis
selective estrogen receptor modulator (SERM), an agent that activates some estrogen receptors but not others, thereby having estrogen-like effects on target tissues without affecting other tissues that have estrogen receptors. modulator [mod´u-la″ter] a specific inductor or agent that brings out characteristics peculiar to a definite region. selective estrogen receptor modulator (SERM) an agent that activates some estrogen receptors but not others, thereby having estrogenlike effects on target tissues (such as bone) without affecting other tissues that have estrogen receptors.
selective estrogen receptor modulator Designer estrogen, SERM Therapeutics A drug–eg, idoxifene, raloxifene–Evista®, which, like estrogen, prevents bone loss and ↓ cholesterol but, unlike estrogen, does not
stimulate the endometrium and breast and thus does not ↑ risk of breast and endometrial CA. See Estrogen receptor, Raloxifene. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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