selected ion monitoring


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selected ion monitoring

A term defined in the context of mass spectrometry as the practice of monitoring and recording ion currents at one or more selected ion m/z values with time, rather than recording full mass spectra, as sample is introduced into the ion source. Because the detector is integrating signal for a longer time at the relevant ion, limits of detection can be lowered, at a cost of increased susceptibility of the analysis to unexpected interferences.
References in periodicals archive ?
There was no apparent interference from other compounds present in the sample because of the selectivity of selected ion monitoring.
Selected ion monitoring method for determination of nicotine, cotinine and deuterium-labeled analogs: absence of an isotope effect in the clearance of (S)-nicotine-3',3'-[D.
5) Codeine, morphine, hydrocodone, and hydromorphone are separated without cross-interference and quantitated with deuterated internal standards and selected ion monitoring (SIM).

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