sedative

(redirected from sedative drug)
Also found in: Dictionary, Thesaurus, Legal, Encyclopedia, Wikipedia.

sedative

 [sed´ah-tiv]
1. allaying irritability, excitement, or nervousness.
2. an agent that does this. The usual mode of action is depression of the central nervous system, which tends to cause lassitude and reduced mental activity. Sedatives are distinct from tranquilizers, which also have a calming effect but unlike sedatives usually do not suppress bodily reactions. Sedatives may be classified according to the organ most affected, such as cardiac, gastric, and so on. Called also calmative.



The degree of relaxation produced varies with the kind of sedative, the dose, the means of administration, and the mental state of the patient. By causing relaxation, a sedative may help a patient go to sleep, but it does not put him to sleep. Medicines that induce sleep are known as hypnotics (some drugs act as sedatives in small amounts and as hypnotics in large amounts). The barbiturates, such as phenobarbital, are the best known sedatives and are also widely used as hypnotics. Other effective sedatives include paraldehyde and chloral hydrate. Sedatives are useful in the treatment of any condition in which rest and relaxation are important to recovery. Some sedatives are also useful in treatment of convulsive disorders or epilepsy and in counteracting the effect of convulsion-producing drugs. They are used to calm patients before childbirth or surgery. Restlessness in invalids, profound grief in adults, and overexcitement in children can be controlled by medically supervised sedation. Because many sedatives are habit-forming, they should be used with caution.

sed·a·tive

(sed'ă-tiv),
1. Calming; quieting.
2. A drug that quiets nervous excitement; designated according to the organ or system on which specific action is exerted; for example, cardiac, cerebral, nervous, respiratory, spinal.
[L. sedativus; see sedation]

sedative

/sed·a·tive/ (sed´ah-tiv)
1. allaying irritability and excitement.
2. a drug that so acts.

sedative

(sĕd′ə-tĭv)
adj.
Having a soothing, calming, or tranquilizing effect; reducing or relieving anxiety, stress, irritability, or excitement.
n.
An agent or a drug having a soothing, calming, or tranquilizing effect.

sedative

[sed′ətiv]
Etymology: L, sedatio, soothing
1 adj, pertaining to a substance, procedure, or measure that has a calming effect.
2 n, an agent that decreases functional activity, diminishes irritability, and allays excitement. Some sedatives have a general effect on all organs; others principally affect the activities of the heart, stomach, intestines, nerve trunks, respiratory system, or vasomotor system. See also sedative-hypnotic.

sedative

Herbal medicine
noun Nervine, see there.
 
Pharmacology
Any agent that acts on the CNS to attenuate responses to stimuli.
 
Activities of sedatives
Anxiolytic, sedative, anticonvulsant.
 
Adverse effects
Ataxia, loss of inhibitions, cardiac and respiratory depression, mental and physical dependence and/or tolerance.
 
Examples
Amobarbital, butabarbital, chlordiazepoxide, diazepam, ethchlorvynol, flurazepam, meprobamate, methyprylon, nordiazepam, pentobarbital, trichlorethanol.

Psychiatry adjective
Calming.

sedative

adjective Calming noun Pharmacology Any agent that acts on the CNS to attenuate responses to stimuli Activities Anxiolytic, sedative, anticonvulsant Adverse effects Ataxia, loss of inhibitions, cardiac and respiratory depression, psychologic and physical dependence, tolerance Examples Amobarbital, butabarbital, chlordiazepoxide, diazepam, ethchlorvynol, flurazepam, meprobamate, methyprylon, nordiazepam, pentobarbital, trichlorethanol

sed·a·tive

(sed'ă-tiv)
1. Calming; quieting.
2. A drug that quiets nervous excitement; designated according to the organ or system on which specific action is exerted, e.g., cardiac, cerebral, nervous, respiratory, spinal.

Sedative

Medicine that has a calming effect and may be used to treat nervousness or restlessness.

sedative,

n a substance that reduces excitability and calms the nervous system.

sed·a·tive

(sed'ă-tiv)
1. Calming; quieting.
2. Drug that quiets nervous excitement; designated according to organ or system on which specific action is exerted.

sedative (sed´ətiv),

n 1. production of sedation. A drug that can produce sedation.
2. a drug that produces cortical depression of varying degrees.
3. a remedy that allays excitement and slows down the basal metabolic rate without impairing the cerebral cortex.
sedative-hypnotic,
n a drug that reversibly depresses the activity of the central nervous system, used mainly to induce sleep and allay anxiety.

sedative

1. allaying irritabiliy and excitement.
2. an agent that calms nervousness, irritability and excitement. In general, sedatives depress the central nervous system and tend to cause lassitude and reduced mental activity. They may be classified, according to the organ most affected, as cardiac, gastric, etc.
The degree of relaxation produced varies with the kind of sedative, the dose, the means of administration, and the mental state of the patient. By causing relaxation, a sedative may help an animal go to sleep, but it does not 'put it to sleep', a dangerous lay euphemism for euthanasia. Medicines that induce sleep are known as hypnotics. A drug may act as a sedative in small amounts and as a hypnotic in large amounts.
The barbiturates such as phenobarbital are the best-known sedatives. They are also widely used as hypnotics. Other effective sedatives are the bromides, paraldehyde and chloral hydrate.
References in periodicals archive ?
Future studies should focus on development of sedation protocols that will allow optimal usage of available sedative drugs to meet the increased sedation requirements in this important subgroup of patients.
It refers to a series of withdrawal symptoms known as withdrawal syndrome caused by sudden withdrawal of illicit or prescription drugs, sedative drugs and opioids used in conventional treatment in ICU, or alcohol in patients who have developed tolerance to and physical and psychological dependence on the drugs or alcohol over long-term use.
This reflects the high frequency of drug use in our community with more than three per cent of Dundee's adults using powerful sedative drugs on a regular basis.
A WOMAN called Shona Sibary wrote an article this week about how she regularly gives her children sedative drugs on long plane journeys.
Ahmadi-Moqaddam added that another act of negligence can be that he was prescribed sedative drugs by the prison's health center and when he was handed over to Iran's Cyber Police, he was not allowed to take them because the necessary prescription and the permit to take them were not available at the time.
The risk of an injurious fall increased even more if the residents were also given hypnotic or sedative drugs as sleeping pills.
Experts say the common trend in the region is for people to get addicted to sedative drugs like hashish, rather than cocaine or heroin.
He noted that Murray said he gave him only 25 milligrams of the drug along with small amounts of benzodiazopines - sedative drugs - to help him sleep.
One of the oldest groups of sedative drugs, the barbiturates, is a derivative of barbituric acid.
In 2007, Dubai customs seized nearly Dh20 million worth of counterfeit sexual stimulants and sedative drugs, the biggest haul in the region.
Music listening is somewhat effective in reducing psychological presented anxiety and volume of sedative drugs required to manage anxiety.
He said: "Ben has not required sedative drugs at any time over the last 24 hours.