secretory granule

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se·cre·to·ry gran·ule

a membrane-bound vesicle, usually containing protein synthesized in the rough endoplasmic reticulum. The protein is delivered to the Golgi complex and is packaged in the trans-Golgi network as secretory granules.


(gran'ul?) [L. granulum, little grain]
1. A small, grainlike mass.
2. In histology, a small intracellular mass that has no apparent internal structure.

acidophil granule

A granule that stains readily with acid dyes.

albuminous granule

A cytoplasmic granule in many normal cells. It is not affected by ether or chloroform, but disappears from view when acetic acid is added.

amphophil granule

Beta granule.

azurophilic granule

A small red or reddish-purple granule that easily takes a stain with azure dyes. Found in lymphocytes and monocytes, it is inconstant in number, being present in about 30% of the cells.

basal granule

Basal body.

basophil granule

A cellular granule that stains with a basic dye.

beta granule

An azurophil granule found in beta cells of the hypophysis or islets of Langerhans of the pancreas that stains with both acid and basic dyes. Synonym: amphophil granule

chromophil granules

Nissl body.

cone granules

The nuclei of the cones, sensory cells of the retina. They form the outer zone of the outer nuclear layer of the retina.

delta granule

A small granule in the delta cells of the pancreas.

eosinophil granule

One of various granules that react with acid dyes. It is present in eosinophils.

glycogen granule

One of the minute particles of glycogen seen in liver cells following fixation.

juxtaglomerular granule

A granule found within the juxtaglomerular cells of the kidneys. Juxtaglomerular cells secrete renin.

Kölliker interstitial granule

A granule in the sarcoplasm of a striated muscle fiber.

metachromatic granule

An irregularly sized granule found in the protoplasm of numerous bacteria. It stains a different color from that of the dye used.

Much granules

See: Much granules

neutrophil granule

Any of the cytoplasmic granules of a neutrophil that often stain a pale blue.

Nissl granules

Nissl bodies.

pigment granule

A granule seen in pigment cells.

Plehn granule

A basophilic granule seen in the conjugating form of Plasmodium vivax.

protein granule

A minute protein particle found in cells.

rod granule

A nucleus of a rod photoreceptor found in the retina.

Schüffner granules

See: Schüffner, Wilhelm A. P.

secretory granule

Zymogen granule.

seminal granule

One of the minute particles in semen, supposed to derive from disintegrated nuclei in nutritive cells from seminiferous tubules.

zymogen granule

A granule present in gland cells, esp. the secretory cells of the pancreas, the chief cells of the gastric glands, and the serous cells of the salivary glands. It is the precursor of the enzyme secreted.
Synonym: secretory granule
References in periodicals archive ?
Secretory granule of the cells did not have a membrane, and the electron density was the lowest among the six types of secretory cells (Fig.
The secretory granule contained vacuoles with various electronic densities (Fig.
There are alternative ways to explain the calcified secretory granules described (Neff 1971a) in the lumen of the calcium-secreting glands in P.
2) If calcified secretory granules are not an artifact of fixation, then they must be dissolved and recrystallized before deposition of the material on the tube aperture.
Importantly, PC1 is active in secretory granules and could therefore be a feature of atrial proBNP processing.
In support of this, the proposed enzymes involved in proBNP maturation are produced predominantly in atrial myocytes (53, 60-62), and the ventricular myocytes do not, at least to the same extent, contain secretory granules for peptide storage and maturation.
In the pituitaries from control rats at all time points after DEN administration, most of the granular cells were of the storage type, characterized by many secretory granules and an inactive appearance, with poor development of endoplasmic reticula (ER) and Golgi complex (Figure 1), as described in detail by others (13,37).
Regarding papillary pituitary adenoma, secretory granules are commonplace, and one would expect to find immunoreactivity for synaptophysin and chromogranin as opposed to TTR and S100 protein.
Cells within the ILCs contained secretory granules characteristic of those seen in islet b cells.
The cytoplasm was more abundant and polarized with the luminal aspect that contained relatively small membrane-bound, moderately dense secretory granules and a well-developed Golgi complex.
The release of inflammatory molecules from these cells is regulated by the activation and phosphorylation of a series of signal transduction molecules, which transmit signals from the cell surface to the secretory granules.