secretory endometrium


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secretory endometrium

Histological changes in the endometrium due to the effects of postovulatory progesterone secretion by the corpus luteum.
See: luteal phase defect; menstrual cycle
See also: endometrium
References in periodicals archive ?
A study22 analysed 2295 endometrial samples from women presenting with AUB from January 1995 to June 2008 and noted that the commonest histopathological diagnosis was secretory endometrium in 571(24.
Endometrial intraepithelial neoplasia occurring alongside secretory endometrium is typically more well differentiated" than is the surrounding background endometrium.
Participants generally performed well on cases of tubal metaplasia and secretory endometrium, with some over-diagnosis of EIN.
In the present study, the most common endometrial histopathology was proliferative endometrium followed by secretory endometrium.
Cyclin D1 staining was evaluated in the glandular epithelium component and in the superficial epithelium component (except carcinoma cases) in each group of proliferative endometrium, secretory endometrium, simple hyperplasia, complex hyperplasia, and adenocarcinoma.
Histopathological Endometrial patterns were classified as Proliferative Endometrium (PE), Secretory Endometrium (SE), Disordered Proliferative Pattern (DPP), Atrophic Endometrium (AE), Endometrial Polyp (EP), Chronic Endometritis (CE), Endometrial Hyperplasia (EH) and Endometrial Carcinoma (CA).
Proliferative endometrium, secretory endometrium, and endometrial hyperplasia without atypia were negative for p53.
They found proliferative endometrium (62%), secretory endometrium (20%), hyperplastic endometrium (13%), irregular ripening (1%), and irregular shedding (1%) on histopathological examination (13).
On hysteroscopy seven cases were found to have irregular uterine cavity, out of which 3 cases showed hyperplastic endometrium (simple hyperplasia-2, complex hyperplasia-1), 2 cases of proliferative, 2 cases of secretory endometrium on histopathology.
In present study, on histopathological examination, 62% patients had proliferative endometrium which may be because of anovulatory nature of DUB in most cases, 20% had secretory endometrium which represents ovulatory type of DUB in these cases (as 15-20% of patients of DUB consistently show evidence of ovulation), 13% had hyperplasia which represents response to unopposed and prolonged estrogen stimulation associated with some cases of chronic anovulation, 3% were in menstrual phase, 1% had irregular shedding and 1% had irregular ripening.
In our study, out of 50 patients, 17 patients had proliferative endometrium, 18 had secretory endometrium, 2 patients showed cystic glandular hyperplasia, 3 patients showed endometrial hyperplasia without dysplasia and no opinion was made in 6 patients because of poor sampling.