As monotherapy for the ordinary type 2 diabetic patient, insulin secretogogues
and metformin appear to have the greatest effect in decreasing hyperglycemia.
The third opportunity is another for Redpoint Bio stems from the company's work in TRPm5 modulators and the discovery of incretin and glucose-dependent secretogogues
This study revealed that the mechanism by which AFTC act as insulin secretogogue
may not be exactly same as that of tolbutamide.
Intracellular calcium regulation during secretogogues
stimulation of the parietal cells.
Topics covered include ensuring quality results in a global testing system; historical background, physiology, typical use, and side effects of anabolic-androgenic steroids; testing for anabolic agents; the art of ferreting out a designer steroid; carbon isotope ratio analysis; stimulants, diuretics, and masking of doping in sport; detection in urine of erythropoietin doping; erythrocyte volume expansion and human performance; growth hormone, secretogogues
, and related issues; gene doping; therapeutic gene use; and doping and its impact on the healthy athlete.
Sulfonylureas are known as insulinotropic agents, insulin releaser agents, or secretogogues
because they stimulate the pancreas to secrete insulin.
Alpha-GPC holds more promise for delivery on this concept because of a lower dose needed to release hGH than amino acids or other secretogogues
Alpha glucosidase inhibitors and nonsulfonylurea secretogogues
are probably somewhat less efficacious; combinations of medications seem to be additive.
Gastrointestinal peptide hormones, gastrin in particular, are potent calcitonin secretogogues
i] induced by various secretogogues
in adrenal medullary cells.