secretin test

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secretin test,

a test of pancreatic function after stimulation with the hormone secretin. The test measures the volume and bicarbonate concentration of pancreatic secretions. Normal volume findings are 2 to 4 mL/kg body weight HCO₃ (bicarbonate): 90 to 130 mEq/L. A lower than normal volume suggests an obstructing malignancy or cystic fibrosis. Reduced bicarbonate and amylase concentration is usually diagnostic of chronic pancreatitis.

secretin

a hormone secreted by the mucosa of the duodenum and jejunum when acid chyme enters the intestine; carried by the blood, it stimulates the secretion of pancreatic juice and, to a lesser extent, bile and intestinal secretion.

secretin test

an examination of the gastric and duodenal contents after intravenous administration of exogenous secretin; useful in the diagnosis of disorders affecting pancreatic exocrine function, for example, pancreatitis and neoplastic disease.

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