secondary outcome measures

secondary outcome measures

The outcome measures in a clinical trial that provide information on therapeutic effects of secondary importance, side effects or tolerability. Data on secondary outcomes are used to evaluate additional effects of the intervention not included in the primary outcome measure.
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Secondary outcome measures include examining objective response, duration of response, clinical benefit, progression-free survival, and time to progression.
Secondary outcome measures and additional trial details and updates can be found at: http://www.
Secondary outcome measures were systolic BP (SBP) and diastolic BP (DBP) at the end of treatment.
The primary outcome measures of externalizing and internalizing behavior problems were reported by both caregivers and their children in a laboratory setting at 0 months (baseline), 6 months (end of treatment) and 12 months (6 months post treatment), together with the secondary outcome measures of parental antisocial behavior.
Secondary outcome measures were stroke, stroke and ischaemic heart disease combined, and mortality.
There also were no differences between the groups in scores on secondary outcome measures, including the Brief Pain Inventory which measures pain-related interference with activities; the Swiss Spinal Stenosis Questionnaire (SSSQ), which measures pain, function, and satisfaction with treatment; the EQ-5D, which measures quality of life; or the Generalized Anxiety Disorder-7 scale.
ORLANDO -- Duloxetine for the treatment of late-life depression missed its primary end point in a recent large randomized trial, but it did result in consistently significant clinical improvement, compared with placebo across numerous secondary outcome measures.
Another strategy was to focus on statistically significant results from secondary outcome measures or subgroup analyses (which have potential for error), while ignoring or downplaying the nonsignificant results of the prespecified primary outcome.
Secondary outcome measures were volume ratio (the volume of the affected arm divided by the volume of the unaffected arm), and a survival analysis over the 4 assessment times of 1, 3, 6 and 12 months.
Secondary outcome measures included the participants' subjectively rated pain, perceived incision healing (VAS Scales), and baseline and post-surgical functional health status (SF-36).
The primary outcome measure was pain relief, and secondary outcome measures were analgesic requirements, hospitalisation and markers of oxidative stress.