secondary malignancy

metastatic cancer

Cancer which has spread in a non-contiguous fashion—by the blood, haematogenously; by the lymphatic, trans-coelomically—from a primary site of origin to a distant site.

secondary malignancy

Oncology A cancer that arises in the background of another malignancy treated by RT or chemotherapy; SM is also defined as one caused by environmental toxins, physical agents, radiation Examples ANLL–eg, AML, acute promyelocytic leukemia, acute monocytic leukemia, erythroleukemia and myelodysplastic disorders–preleukemia Leukemogenic chemotherapeutics Chlorambucil, melphalan and, combined, doxorubicin, cisplatin Physical agents causing SM–Radiation–solar, X-rays to head & neck causes 2º BCCs; latency period to 2º neoplasm 3-65 yrs Chronic irritation–Marjolin's ulcer causing skin cancer or chronic injury–eg, heat-induced SCC Scar malignancy–eg, malignant fibrous histiocytoma arising in sites with metal objects or shrapnel or malignancy induced by mechanical trauma, a relation which in humans is anecdotal, ischemia and SCC near varicose veins. See Occult primary.

Patient discussion about secondary malignancy

Q. I have met my close friend after 3 years. She is showing some signs of high depression. How can I help her? I have met my very close friend after 3 years and she is very depressed. I am worried that she is showing some signs of high depression. She talks all rubbish and negatives these days which is filled with that nonsense hopelessness. She was fine and going good when I left her and now she is completely negative in her behavior and also very depressed. She is not able to enjoy my company. She had lost her weight and her eyes reflect the bluntness. She keeps silent most of the time. How can I help her?

A. I think first you must talk to her and find out about when and how this started. Take her to all the places where you both used to go. She might have come across difficult phase in these years which would have made her depressed and she may need a support to bring her back to normal way of living. We cannot say that this is a depression which would get cured by just talking and knowing the reasons but you must help her to fight back for the thing she had lost. If there is no desired result, then do consult a physician.
http://www.youtube.com/watch?v=P9QxddJOQY4&eurl=http://www.imedix.com/health_community/vP9QxddJOQY4_nervous_system_depression_psyche?q=depression&feature=player_embedded

Q. Does staging in breast cancer is linked to metastasis and what is the use of staging?

A. stages in cancer tell of it's progress. is it benign, does it have a capsule, did it metastasized and all that. but if you are looking for more accurate and more information on that in general:
http://www.breastcancer.org/symptoms/diagnosis/staging.jsp

this should do it!

Q. What is the best pathophysiology of colorectal cancer. The pathophysiology just has to be brief and concise. It also has to include nursing considerations for the patient.

A. i'm not sure i understand your question...do you mean what is the best treatment for colorectal cancer? patophysiology is the changes the tissue acquired. if you'll give me more details on what you are looking for i'll be more then happy to help you.

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References in periodicals archive ?
A growing body of evidence has demonstrated the cost effectiveness of PBT for children and adults when improvements in quality of life, reductions in the risk of a secondary malignancy and fewer long and short term side effects are considered.
The most frequent complications include infection, autoimmune disorders, and secondary malignancy (3).
Ruling out the possibility of secondary malignancy is a necessary step for diagnosing primary bladder adenocarcinoma and can be very challenging for the pathologist.
The most frequent secondary malignancy to involve the urinary bladder is colorectal adenocarcinoma.
In our patient, mediastinal enlargement was observed initially and CT was performed considering secondary malignancy because of a history of long-term and intensive immunosupressive treatment.
In the second case, the very short latency period between the diagnosis of the NHL and the occurrence of the secondary malignancy as well as the discrete bone marrow changes at the bone marrow examination after occurrence of bicytopenia raised the suspicion of tMDS.
13,15) Recently, mercaptopurine has been also implicated in inducing a secondary malignancy.
Secondary malignancy metastatic to the breast is uncommon with an incidence of 0.
Of course, it is important to consider the side effects of aggressive chemotherapy, which include secondary malignancy, sepsis, azoospermia, and immunosuppression.
1] Endoscopy is a less reliable technique than barium studies in the diagnosis of linitis plastica in the stomach due to either primary or secondary malignancy, because the overlying mucosa can appear normal and tumor cells are predominantly located in the submucosa and are often separated by large areas of fibrosis.
Because the lateral parotid region had been included in the original radiotherapy field, reirradiation would have subjected the patient to an increased risk of soft tissue and bone radio-necrosis, as well as an increased chance of a secondary malignancy.

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