secondary malignancy

metastatic cancer

Cancer which has spread in a non-contiguous fashion—by the blood, haematogenously; by the lymphatic, trans-coelomically—from a primary site of origin to a distant site.

secondary malignancy

Oncology A cancer that arises in the background of another malignancy treated by RT or chemotherapy; SM is also defined as one caused by environmental toxins, physical agents, radiation Examples ANLL–eg, AML, acute promyelocytic leukemia, acute monocytic leukemia, erythroleukemia and myelodysplastic disorders–preleukemia Leukemogenic chemotherapeutics Chlorambucil, melphalan and, combined, doxorubicin, cisplatin Physical agents causing SM–Radiation–solar, X-rays to head & neck causes 2º BCCs; latency period to 2º neoplasm 3-65 yrs Chronic irritation–Marjolin's ulcer causing skin cancer or chronic injury–eg, heat-induced SCC Scar malignancy–eg, malignant fibrous histiocytoma arising in sites with metal objects or shrapnel or malignancy induced by mechanical trauma, a relation which in humans is anecdotal, ischemia and SCC near varicose veins. See Occult primary.

Patient discussion about secondary malignancy

Q. I have met my close friend after 3 years. She is showing some signs of high depression. How can I help her? I have met my very close friend after 3 years and she is very depressed. I am worried that she is showing some signs of high depression. She talks all rubbish and negatives these days which is filled with that nonsense hopelessness. She was fine and going good when I left her and now she is completely negative in her behavior and also very depressed. She is not able to enjoy my company. She had lost her weight and her eyes reflect the bluntness. She keeps silent most of the time. How can I help her?

A. I think first you must talk to her and find out about when and how this started. Take her to all the places where you both used to go. She might have come across difficult phase in these years which would have made her depressed and she may need a support to bring her back to normal way of living. We cannot say that this is a depression which would get cured by just talking and knowing the reasons but you must help her to fight back for the thing she had lost. If there is no desired result, then do consult a physician.
http://www.youtube.com/watch?v=P9QxddJOQY4&eurl=http://www.imedix.com/health_community/vP9QxddJOQY4_nervous_system_depression_psyche?q=depression&feature=player_embedded

Q. Does staging in breast cancer is linked to metastasis and what is the use of staging?

A. stages in cancer tell of it's progress. is it benign, does it have a capsule, did it metastasized and all that. but if you are looking for more accurate and more information on that in general:
http://www.breastcancer.org/symptoms/diagnosis/staging.jsp

this should do it!

Q. What is the best pathophysiology of colorectal cancer. The pathophysiology just has to be brief and concise. It also has to include nursing considerations for the patient.

A. i'm not sure i understand your question...do you mean what is the best treatment for colorectal cancer? patophysiology is the changes the tissue acquired. if you'll give me more details on what you are looking for i'll be more then happy to help you.

More discussions about secondary malignancy
References in periodicals archive ?
Until now, there has not been a relevant large study of Chinese MM patients available to study SPMs, and no secondary malignancy after bortezomib treatment alone has been reported.
Objective: Secondary malignancy is a major life-threatening complication facing patients afflicted with acquired immunodeficiency syndrome (AIDS).
The subjects received chemotherapy within three months of diagnosis and had no secondary malignancy within a year.
Monitor patients at every visit for late-onset treatment effects that can produce pain, just as they are monitored for recurrent disease and secondary malignancy.
In urinary diversion using isolated gut segment, secondary malignancy as adenocarcinomas resulting of the irritation of the intestinal mucosa by the contact with urine is not uncommon, which has been rarely reported and is a secondary malignancy as urothelial carcinoma.
The risk of secondary malignancy following RT is related to overall survival time.
A secondary malignancy could be defined as a new cancer that has occurred as a result of previous treatment with radiation or chemotherapy.
Final diagnosis depending on this histopathology was made as malignant melanoma arising as a secondary malignancy in teratomatous component of PMGCT.
4%), thrombocytopenia may be related directly to HIV infection, adverse effect of drug therapy, or secondary malignancy or myelodysplasia.
Ruling out the possibility of secondary malignancy is a necessary step for diagnosing primary bladder adenocarcinoma and can be very challenging for the pathologist.
In our patient, mediastinal enlargement was observed initially and CT was performed considering secondary malignancy because of a history of long-term and intensive immunosupressive treatment.
In the second case, the very short latency period between the diagnosis of the NHL and the occurrence of the secondary malignancy as well as the discrete bone marrow changes at the bone marrow examination after occurrence of bicytopenia raised the suspicion of tMDS.

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