Lymph nodes are the most specialized secondary lymphoid organ
secondary lymphoid organ
, is also associated with accelerated atherosclerosis
2008) Autotaxin, an ectoenzyme that produces lysophosphatidic acid, promotes the entry of lymphocytes into secondary lymphoid organs
Damage to primary and secondary lymphoid organs
will result in impaired immune functioning.
The thymus and bone marrow are considered to be primary lymphoid organs because they are maturation sites for the cells, which move into the secondary lymphoid organs
where they serve to protect the body against foreign antigens.
In this DOCK2 knockout mouse, the function of activating Rac to mediate actin cyteskeleton, the lymphocyte migration function in response to stimuli with chemokines such as SLC, SDF-1, BLC, the homing function to secondary lymphoid organs
such as spleen, lymph nodes and Peyer's patches, and the function of emigrating mature thymic T cells into peripheral blood in response to stimulus with chemokine ELC are impaired, and as a result of this, immune responses are suppressed.
In most circumstances, if one looks hard enough, there is evidence that the virus is still probably replicating at very low levels in immune-privileged sites such as the brain and testes and in secondary lymphoid organs
Their job is to take up antigens and transport them to secondary lymphoid organs
for activation of specific T cells.
According to current concepts of the normal Immoral immune system, all B lymphocytes arise from pluripotent stem cells in the bone marrow and then subsequently migrate to secondary lymphoid organs
such as lymph node follicles and Peyer patches in the gastrointestinal tract.
Mature lymphocytes populate the secondary lymphoid organs
, such as lymph nodes, spleen and circulating lymph.