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secondary lymphoid organ

    0.01 sec.
secondary lymphoid organ,
a source of effector lymphocytes, such as the spleen, lymph nodes, or tonsils.


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In contrast, hyper-IgE production depends on Th2-like profile of circulating memory/effector T cells that home to secondary lymphoid organs.
In this DOCK2 knockout mouse, the function of activating Rac to mediate actin cyteskeleton, the lymphocyte migration function in response to stimuli with chemokines such as SLC, SDF-1, BLC, the homing function to secondary lymphoid organs such as spleen, lymph nodes and Peyer's patches, and the function of emigrating mature thymic T cells into peripheral blood in response to stimulus with chemokine ELC are impaired, and as a result of this, immune responses are suppressed.
Chemokines, or chemotactic cytokines, and their receptors have been discovered as essential and selective mediators in leukocyte migration to inflammatory sites and to secondary lymphoid organs.
 
 
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