secondary immunodeficiency

(redirected from secondary hypogammaglobulinemia)

sec·on·dar·y im·mu·no·de·fi·cien·cy

immunodeficiency with no evident defect in the lymphoid tissues, but rather hypercatabolism or loss of immunoglobulins such as occurs in familial idiopathic hypercatabolic hypoproteinemia, protein-losing enteropathy, nephrotic syndrome, uremia, malnutrition, infection, diabetes, or malignancy.

secondary immunodeficiency

a loss of immunity caused by a disease process or toxic effect of medication rather than by a failure or defect in T or B lymphocytes.

sec·on·dary im·mu·no·de·fi·cien·cy

(sekŏn-dār-ē imyū-nō-dĕ-fishĕn-sē)
Form with no evident defect in the lymphoid tissues, but rather hypercatabolism or loss of immunoglobulins.
Synonym(s): secondary agammaglobulinemia, secondary hypogammaglobulinemia.
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References in periodicals archive ?
18 years) with primary immunodeficiency syndromes and myeloma or chronic lymphocytic leukemia (CLL) with severe secondary hypogammaglobulinemia and recurrent infections.
The majority of infections were due to upper-respiratory tract and urinary tract infections, possibly associated with secondary hypogammaglobulinemia.
In Europe it is indicated for treating: primary immunodeficiency, primary immune thrombocytopenic purpura, Guillain-Barre syndrome, Kawasaki disease, replacement therapy in multiple myeloma or chronic lymphocytic leukemia with secondary hypogammaglobulinemia and recurrent infections, replacement therapy in children with congenital AIDS and recurrent infections, and allogeneic haematopoietic stem cell transplantation (HSCT) in patients with secondary hypogammaglobulinemia.

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