secondary amyloidosis


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Related to secondary amyloidosis: primary amyloidosis, AA amyloidosis

sec·on·dar·y am·y·loi·do·sis

amyloidosis occurring in association with another chronic inflammatory disease; organs chiefly involved are the liver, spleen, and kidneys, and the adrenal glands less frequently.

secondary amyloidosis

sec·on·dar·y am·y·loid·o·sis

(sek'ŏn-dar-ē am'i-loy-dō'sis)
Amyloidosis occurring in association with another chronic inflammatory disease; organs chiefly involved are the liver, spleen, and kidneys; the suprarenal glands less frequently.

sec·on·dary am·y·loid·o·sis

(sek'ŏn-dar-ē am'i-loy-dō'sis)
Amyloidosis occurring in association with another chronic inflammatory disease; organs chiefly involved are the liver, spleen, and kidneys.

amyloidosis

the deposition in various tissues of amyloid. This protein is almost insoluble and once it infiltrates the tissues they become waxy and nonfunctioning. Systemic amyloidosis may be immunocytic or reactive (see below).

cutaneous amyloidosis
multiple cutaneous, hard, painless, chronic plaques occur over the head, neck and shoulders of horses. There may be involvement of the nasal mucosa and resulting dyspnea.
familial renal amyloidosis of Shar pei dogs
manifested by episodic fever and swelling of one or both hocks which may resolve spontaneously, but is recurring. The condition is resistant to treatment and eventually there is renal and/or hepatic failure.
immunocytic amyloidosis, immunogenic amyloidosis, primary amyloidosis
amyloid produced from light chains of immunoglobulins as in plasma-cell dyscrasias. See also al protein.
reactive amyloidosis
is derived from excess serum protein SAA produced as a result of chronic antigenic stimulation. The kidney is most often affected and the amyloid is most often deposited in glomeruli but medullary deposits are seen in cats and cattle. Idiopathic amyloidosis is common in the dog and less common in cats. It is associated with chronic suppurative disease processes in cattle, antiserum production in horses, and it occurs rarely in pigs. Called also secondary alopecia.
renal amyloidosis
characterized by severe proteinuria and uremia. There is chronic diarrhea, polydipsia and anasarca. Seen particularly in dogs and cats.
secondary amyloidosis
reactive amyloidosis (above).
References in periodicals archive ?
4) The prognosis of FMF with the development of secondary amyloidosis is often good but depends on the severity of any damage resulting from amyloidosis and if treatment has been appropriately provided.
Secondary amyloidosis is associated with chronic inflammatory diseases such as FMF.
If colchicine treatment is provided within reasonable time, the accumulation of amyloid protein in the tissue can be impeded and secondary amyloidosis prevented or reversed (dependent on the severity).
3) Thus, a lack of awareness of a population for FMF would lead to an increased rate of secondary amyloidosis.
Decrease in the rate of secondary amyloidosis in Turkish children with FMF: are we doing better?
The study will evaluate the efficacy and safety of the orally active anti-amyloid treatment, Fibrillex(TM), in patients suffering from Secondary Amyloidosis," said Dr.
Secondary Amyloidosis is a systemic and fatal form of amyloidosis.
Neurochem's research team has been working with international amyloid experts on the development of therapeutic cures to amyloid-related diseases, including Alzheimer's Disease, Secondary Amyloidosis, Diabetes Type II and Hemorrhagic Stroke due to Cerebral Amyloid Angiopathy.
56% of cases of amyloid goiter were caused by secondary amyloidosis (6).
Although no effective medical treatment exists for either form of amyloidosis, confirmation of the type by immunohistochemical techniques is important, since patients with secondary amyloidosis tend to have a better prognosis than those suffering from primary amyloidosis (1,2), due to controllable underlying condition.
Current lead product candidates advanced by Neurochem include Alzhemed(TM), for Alzheimer's Disease, Cerebril(TM), for Hemorrhagic Stroke (due to Cerebral Amyloid Angiopathy), and Fibrillex(TM), for Secondary Amyloidosis.