sea-blue histiocyte syndrome


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sea-blue histiocyte syndrome

a condition of spleen enlargement and mild thrombocytopenia. Histiocytes in the bone marrow contain cytoplasmic granules that stain bright blue.
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Sea-blue histiocyte
An autosomal recessive [MIM 269500] condition characterised by abundant sea-blue histiocytes, with hepatosplenomegaly, thrombocytopenia and masses of histiocytes in the skin, lungs, gastrointestinal tract and central nervous system with compromised function