FOXP3

(redirected from scurfin)

FOXP3

A gene on chromosome Xp11.23 that encodes a member of the forkhead/winged-helix family of transcriptional regulators.

Molecular pathology
FOXP3 mutations cause immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) (X-linked autoimmunity-immunodeficiency syndrome).
References in periodicals archive ?
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse.