scopolamine


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scopolamine

 [sko-pol´ah-mēn]
an anticholinergic and antimuscarinic alkaloid derived from various plants, having a depressant effect on the central nervous system. Used as an antisialagogue preanesthetic medication and as an adjunct to general anesthesia, administered parenterally; as an antiemetic, administered orally or parenterally; and as a cycloplegic and mydriatic, applied topically to the conjunctiva. Called also hyoscine.

sco·pol·a·mine

(skō-pol'ă-mēn, -min),
An alkaloid found in the leaves and seeds of Hyoscyamus niger, Duboisia myoproides, Scopolia japonica, S. carniolica, Atropa belladonna, and other solanaceous plants; exerts anticholinergic actions similar to that of atropine, but is thought to have greater central nervous system effects; useful in preventing motion sickness; available as various salts.
Synonym(s): hyoscine

scopolamine

/sco·pol·a·mine/ (sko-pol´ah-mēn) an anticholinergic alkaloid obtained from various solanaceous plants; used as the base or the hydrobromide salt as an antiemetic and as the hydrobromide salt as a preanesthetic antisialagogue, adjunct to general anesthesia, and topical mydriatic and cycloplegic.

scopolamine

(skə-pŏl′ə-mēn′, -mĭn)
n.
An alkaloid drug, C17H21NO4, extracted from plants such as henbane and used primarily to treat motion sickness and nausea and to dilate the pupil. Also called hyoscine.

scopolamine

[skōpol′əmēn]
Etymology: Giovanni A. Scopoli, Italian naturalist, 1723-1788
an anticholinergic alkaloid obtained from the leaves and seeds of several solanaceous plants. It is a central nervous system depressant.
indications It is prescribed for prevention of motion sickness and as an antiemetic, a sedative in obstetrics, and a cycloplegic and mydriatic.
contraindications Narrow-angle glaucoma, asthma, myasthenia gravis, obstruction of the genitourinary or GI tract, severe ulcerative colitis, and known hypersensitivity prohibit its use.
adverse effects Among the more serious adverse effects are blurred vision, central nervous system effects, tachycardia, dry mouth, decreased sweating, and hypersensitivity reaction. Also called hyoscine. See also transdermal scopolamine.

scopolamine

®Therapeutics An atropine-like anticholinergic–or antimuscarinic, used in preanesthesia, where CNS depression is desirable, GI tract antispasmodic, to ↑ heart rate, and counteract vasodilation and low BP caused by choline esters Metabolism GI tract absorption,12 metabolized in liver, remainder in kidneys Adverse efects Dry mouth, tachycardia, palpitation, pupillary dilatation, blurring of vision, headache, dry
hot skin

sco·pol·a·mine

(skō-pol'ă-mēn)
An alkaloid found in the leaves and seeds of Hyoscyamus niger, and other solanaceous plants; exerts anticholinergic actions similar to that of atropine, but thought to have greater central nervous system effects; useful in preventing motion sickness; available as various salts.
Synonym(s): hyoscine.

scopolamine

An ATROPINE-like drug used in premedication as a sedative and to dry up respiratory and salivary secretions.

sco·pol·a·mine

(skō-pol'ă-mēn, -min)
An alkaloid found in the leaves and seeds of various plants; exerts anticholinergic actions similar to that of atropine, but is thought to have greater central nervous system effects; useful in preventing motion sickness.
Synonym(s): hyoscine.

scopolamine (skōpol´əmēn),

n an alkaloid found in the leaves and seeds of
Atropa belladonna and other solanaceous plants having an action similar to atropine and used when spasmolytic or antisecretory effects are desired.
scopolamine, transdermal,
brand names: Transderm-Scōp, Transderm-V;
drug class: antiemetic, anticholinergic;
action: competitive antagonism of acetylcholine at receptor sites in the eye, smooth muscle, cardiac muscle, glandular cells; inhibition of vestibular input to the central nervous system (CNS), resulting in inhibition of vomiting reflex;
use: prevention of motion sickness.

scopolamine

an anticholinergic alkaloid derived from various plants, used as the hydrobromide in parasympathetic blockade and as a central nervous system depressant.
References in periodicals archive ?
Histamine H(3)-receptor antagonism improves memory retention and reverses the cognitive deficit induced by scopolamine in a two-trial place recognition task.
In order to limit saliva production, a scopolamine transdermal release system was applied to the hairless skin overlying the parotid region.
Neither Ninjin-yoei-to nor scopolamine had any significant effect on the paw-licking latency.
The availability of scopolamine gel is limited because it must be prepared in a pharmacy that has trained compounding specialists Broidy remarked.
SANTIAGO, CHILE -- Treatment with scopolamine hydrobromide blocks muscarinic cholinergic receptors and produces a rapid, robust antidepressant response in depressed patients with unipolar or bipolar depression, Maura L.
Then for scopolamine, when they charged people like Dick Mandella and Willard Proctor-and now this.
Visitors sometimes are slipped the disorienting drug scopolamine in drinks, cigarettes, gum and even on powder-laced paper.
They have been used since the early 1980's to administer such drugs as scopolamine ,effective against motion sickness, nicotine, for cigarette withdrawal, and nitro- glycerin for angina .
The three most common medications that are used are scopolamine (scoh-POH-lah-meen), glycopyrrolate (glye-coh-PIE-roh-late) and atropine sulfate (EH-troh-peen suhl-fate).
Robinul, Donnatal, Levsin, atropine, scopolamine, Pamine, Quarzan, Tral, Darbid, Cantil, Bathine, Pro-Banthine, Pathilon, Bentyl, Daricon, Ditropan, various combination products
So does scopolamine, the stuff that keeps you from getting sick on those long rides in the car.
The anti-diarrhea product Donnagel cannot contain atropine sulfate, hyoscyamine sulfate, or scopolamine hydrobromide.