panencephalitis

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Related to sclerosing panencephalitis: Measles encephalitis

panencephalitis

 [pan″en-sef″ah-li´tis]
encephalitis, probably of viral origin, that produces intranuclear or intracytoplasmic inclusion bodies that result in parenchymatous lesions of both the gray and white matter of the brain.

pan·en·ceph·a·li·tis

(pan'en-sef'ă-lī'tis),
A diffuse inflammation of the brain.

panencephalitis

/pan·en·ceph·a·li·tis/ (pan″en-sef″ah-li´tis) encephalitis, probably of viral origin, which produces intranuclear or intracytoplasmic inclusion bodies that result in parenchymatous lesions of both the gray and white matter of the brain.

panencephalitis

(păn′ĕn-sĕf′ə-lī′tĭs)
n.
1. Encephalitis that affects both gray and white matter of the brain, resulting in progressive loss of mental and motor functions.
2. Subacute sclerosing panencephalitis.

panencephalitis

[pan′ənsef′əlī′tis]
Etymology: Gk, pan + enkephale, brain, itis
inflammation of the entire brain characterized by an insidious onset, a progressive course with deterioration of motor and mental functions, and evidence of a viral cause. One example is subacute sclerosing panencephalitis, an uncommon childhood disease thought to be caused by a "slow" latent measles virus after recovery from a previous infection. Most of the patients are younger than 11 years of age, and many more boys than girls are affected. The disease results in ataxia, myoclonus, atrophy, cortical blindness, and mental deterioration. Antiviral drugs, immunosuppressants, and interferon inducers are sometimes administered, but the disease is usually unremitting and fatal.

panencephalitis

Simultaneous inflammation of the gray and white matter. See Subacute sclerosing panencephalitis.

pan·en·ceph·a·li·tis

(pan'en-sef'ă-lī'tis)
A diffuse inflammation of the brain.

panencephalitis

An ENCEPHALITIS involving the grey and white matter simultaneously. A very severe form affecting children is caused by a MYXOVIRUS (subacute sclerosing panencephalitis).

panencephalitis

encephalitis with parenchymatous lesions of both the gray and white matter of the brain.

sclerosing panencephalitis
see old dog encephalitis.
References in periodicals archive ?
Changing epidemiological features of subacute sclerosing panencephalitis.
The elctroencephalogram in subacute sclerosing panencephalitis.
Subacute sclerosing panencephalitis with atypical onset: clinical, computed tomographic and magnetic resonance imaging correlations.
Jabbour JT, Duenas DA, Sever JL et al: Epidemiology of subacute sclerosing panencephalitis (SSPE).
Quantification of measles virus specific immunoglobulins in serum, CSF and brain extract from patients with subacute sclerosing panencephalitis.
An immunohistochemical study of the distribution of the measles virus receptors, CD46 and SLAM, in normal human tissues and subacute sclerosing panencephalitis.
Use of a brief assessment examination in a study of subacute sclerosing panencephalitis.
Subacute sclerosing panencephalitis is typically characterized by alterations in the fusion protein cytoplasmic domain of the persisting measles virus.
The third form, subacute sclerosing panencephalitis (SSPE), manifests 2-10 years after primary measles infection as a progressive and fatal chronic neurodegenerative disease caused by persistent defective measles virus in neurons and oligodendrocytes.
Expression of defective measles virus genes in brain tissues of patients with subacute sclerosing panencephalitis.
Subacute sclerosing panencephalitis (SSPE), a postinfectious neurologic complication of measles, can also occur.
Symposium to ICNA/CNS Subacute Sclerosing Panencephalitis meeting: Update.