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panencephalitis
(redirected from sclerosing panencephalitis)

   Also found in: Dictionary/thesaurus 0.01 sec.
panencephalitis /pan·en·ceph·a·li·tis/ (pan″en-sef″ah-li´tis) encephalitis, probably of viral origin, which produces intranuclear or intracytoplasmic inclusion bodies that result in parenchymatous lesions of both the gray and white matter of the brain.
pan·en·ceph·a·li·tis (pnn-sf-lts)
n.
Encephalitis that affects both the gray and white matter of the brain, resulting in progressive loss of mental and motor functions.

panencephalitis
[pan′ənsef′əlī′tis]
Etymology: Gk, pan + enkephale, brain, itis
inflammation of the entire brain characterized by an insidious onset, a progressive course with deterioration of motor and mental functions, and evidence of a viral cause. One example is subacute sclerosing panencephalitis, an uncommon childhood disease thought to be caused by a "slow" latent measles virus after recovery from a previous infection. Most of the patients are younger than 11 years of age, and many more boys than girls are affected. The disease results in ataxia, myoclonus, atrophy, cortical blindness, and mental deterioration. Antiviral drugs, immunosuppressants, and interferon inducers are sometimes administered, but the disease is usually unremitting and fatal.

panencephalitis [pan″en-sef″ah-li´tis]
encephalitis, probably of viral origin, that produces intranuclear or intracytoplasmic inclusion bodies that result in parenchymatous lesions of both the gray and white matter of the brain.

panencephalitis
encephalitis with parenchymatous lesions of both the gray and white matter of the brain.

sclerosing panencephalitis
see old dog encephalitis.

panencephalitis
Simultaneous inflammation of the gray and white matter. See Subacute sclerosing panencephalitis.


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We studied eight children who had measles at 6 to 10 months of age during the 1998 Argentine measles outbreak and in whom subacute sclerosing panencephalitis developed 4 years later.
In Canada, Imunovir(TM) is registered for the treatment of subacute sclerosing panencephalitis.
5 years of his life in an orphanage in Thailand before adoption by an American couple became ill with subacute sclerosing panencephalitis and died several months later.
 
 
 
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