scleroderma renal crisis


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scleroderma renal crisis

The abrupt onset of kidney failure and severe hypertension in patients with progressive systemic sclerosis. It is treated by controlling blood pressure with angiotensin converting enzyme inhibitors, sometimes in association with other agents.
See also: crisis
References in periodicals archive ?
Scleroderma renal crisis, if diagnosed, deserves a trial of ACE inhibitors even at an advanced stage, with the likelihood of improvement of the kidney function.
Major Finding: Patients with incident scleroderma renal crisis who are on ACE inhibitors prior to the onset of disease do not have worse outcomes than those not on the antihypertensive agents before SRC diagnosis.
Case-control study of corticosteroids and other drugs that either precipitate or protect from the development of scleroderma renal crisis.
Treatment of scleroderma renal crisis must be prompt and symptom-specific, and malignant hypertension, hemolytic anemia, encephalopathy and pulmonary edema are all life-threatening and require prompt aggressive intervention.
Abstract: Scleroderma renal crisis (SRC) has classically been defined as a new onset of accelerated arterial hypertension associated with a rapid increase in serum creatinine concentration and/or microangiopathic hemolytic anemia.
She then talked about treatment of scleroderma renal crisis.