scleroderma renal crisis


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scleroderma renal crisis

The abrupt onset of kidney failure and severe hypertension in patients with progressive systemic sclerosis. It is treated by controlling blood pressure with angiotensin converting enzyme inhibitors, sometimes in association with other agents.
See also: crisis
References in periodicals archive ?
The finding further fuels the ongoing debate over the role of angiotensin-converting enzyme (ACE) inhibitors as prophylaxis for scleroderma renal crisis (SRC), lead investigator Dr.
In the kidneys, injury to the medium-sized arteries can precipitate scleroderma renal crisis (SRC) with malignant hypertension and hyperreninemia, microangiopathic hemolytic anemia, and rapidly progressive renal failure.
Scleroderma renal crisis (SRC) is a life-threatening visceral complication of systemic sclerosis (SSc) characterized by the abrupt onset of malignant hypertension and rapidly progressive, oliguric renal failure.