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scleredema

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scleredema /scle·re·de·ma/ (sklēr″ĕ-de´mah) diffuse, symmetrical, woodlike, nonpitting induration of the skin of unknown etiology, typically beginning on the head, face, or neck and spreading to involve the shoulders, arms, and thorax and sometimes extracutaneous sites.
scleredema neonato´rum  sclerema.

scler·e·de·ma (sklîr-dm)
n.
Hard nonpitting edema of the skin, having a waxy appearance with no sharp demarcation and occurring mainly in females with diabetes mellitus.

scleredema
[sklir′ədē′mə]
Etymology: Gk, skleros + oidema, swelling
an idiopathic skin disease characterized by nonpitting induration beginning on the face or neck and spreading downward over the body, sparing the hands and feet. There also may be tongue swelling, restriction of eye movements, and pericardial, pleural, and peritoneal effusions. Resolution occurs after several months, but recurrences are common. The condition often follows a streptococcal infection or an exanthem of childhood. There is no specific treatment. Compare scleroderma.

scleredema [sklē″rĕ-de´mah]
diffuse, symmetrical, woodlike, nonpitting induration of the skin; it typically begins on the face, head, or neck and spreads progressively to involve the shoulders, arms, thorax, and sometimes extracutaneous sites. The etiology is unknown; it is usually preceded by any of various infectious processes, especially a staphylococcal infection. In most cases it resolves spontaneously.
scleredema neonato´rum sclerema neonatorum.

scleredema
Physical exam A diffuse, symmetrical idiopathic induration of skin which may follow staphylococcal skin infection, associated with DM, and resolve spontaneously


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Lenalidomide may also be useful for paraproteinemia-associated skin disorders, such as multicentric reticulohistiocytosis, scleromyxedema and a subtype of scleredema.
Systemic sclerosis must be differentiated from other conditions associated with skin fibrosis, including localized scleroderma, scleredema, scleromyxedema, and eosinophilic fasciitis, as well as rare conditions (e.
 
 
 
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