MSR1

(redirected from scavenger receptor class A, member 1)

MSR1

A gene on chromosome 8p22 that encodes the class-A macrophage scavenger receptors, which include three different types (1, 2 and 3) generated by alternative splicing of MSR1. The receptor isoforms have been implicated in both macrophage-associated physiological and pathological processes, including atherosclerosis, Alzheimer's disease and host defence.

Molecular pathology
Defects in MSR1 have been linked to an increased susceptibility to prostate cancer and Barrett’s oesophagus.