scavenger receptor


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scavenger receptor

a receptor on macrophages that binds preferentially to oxidized LDL, causing macrophages to internalize the LDL.

scav·en·ger re·cep·tor

(skav'ĕn'jĕr rĕ-sep'tŏr)
A receptor on macrophages that binds preferentially to oxidized low-density lipoprotein (LDL), causing macrophages to internalize the LDL.
References in periodicals archive ?
The cellular uptake of lipid is mediated by many receptors, such as very low-density lipoprotein receptor (VLDLR), low-density lipoprotein receptor protein (LDLR), scavenger receptor (16) and others.
Initiation of hepatitis C virus infection is dependent on cholesterol and cooperativity between CD81 and scavenger receptor B type I.
Association of three polymorphisms of scavenger receptor class BI gene (exon8, exon1, intron5) with coronary stenosis in a coronary Tunisian population.
Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease.
Regulation of scavenger receptor CD163 expression in human monocytes and macrophages by pro- and anti-inflammatory stimuli.
Inhibition of protein kinase Cbeta prevents foam cell formation by reducing scavenger receptor A expression in human macrophages.
Dynamic expression of multiple scavenger receptor cysteine-rich genes in eoelomocytes of the purple sea urchin.
Although controversial, there is evidence that cholesterol returning to the liver in HDL via the scavenger receptor type 131 (SRB1) is preferentially used in the formation of biliary cholesterol that is excreted into the intestines.
Researchers have developed a simple blood test for this variation of the scavenger receptor class B type 1 gene (SCARB1) but emphasized there is no approved therapy yet to address the problem in infertile women.
Testosterone up-regulates scavenger receptor BI and stimulates cholesterol efflux from macrophages.
The presence of the B-type scavenger receptor CD36 in the cell types used was checked by means of immunostaining and RT-PCR procedures.
A more direct delivery of HDL cholesterol is by uptake of HDL through receptors such as the scavenger receptor (SR-B1) that has been shown to promote excretion into the bile.