sarcoplasmic reticulum


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reticulum

 [rĕ-tik´u-lum] (L.)
1. a small network, especially a protoplasmic network in cells.
agranular reticulum smooth-surfaced endoplasmic reticulum.
endoplasmic reticulum an ultramicroscopic organelle of nearly all higher plant and animal cells, consisting of a system of membrane-bound cavities in the cytoplasm, occurring in two types: granular or rough-surfaced, bearing large numbers of ribosomes on its outer surface, and agranular or smooth-surfaced.
granular reticulum rough-surfaced endoplasmic reticulum.
sarcoplasmic reticulum a form of agranular reticulum in the sarcoplasm of striated muscle, comprising a system of smooth-surfaced tubules surrounding each myofibril.

sar·co·plas·mic re·tic·u·lum

the agranular endoplasmic reticulum of skeletal and cardiac muscle; the complex of vesicles, tubules, and cisternae forming a continuous structure around striated myofibrils, with a repetition of structure within each sarcomere.

sarcoplasmic reticulum

n.
The form of endoplasmic reticulum found in striated muscle fibers.

sarcoplasmic reticulum

[-plas′mik]
Etymology: Gk, sarx + plassein, to mold; L, reticulum, little net
a network of tubules and sacs in skeletal muscle fibers that plays an important role in muscle contraction and relaxation by releasing and storing calcium ions. This network is analogous, but not identical, to the endoplasmic reticulum of other cells.

sar·co·plas·mic re·tic·u·lum

(sahr'kō-plaz'mik rĕ-tik'yū-lŭm)
The endoplasmic reticulum of skeletal and cardiac muscle; the complex of vesicles, tubules, and cisterns forming a continuous structure around striated myofibrils, with a repetition of structure within each sarcomere.

sarcoplasmic reticulum

The endoplasmic reticulum of a muscle cell which stores and releases calcium ions.

sarcoplasmic reticulum

the cysternae of a single muscle fibre, equivalent to the ENDOPLASMIC RETICULUM of other cells.
References in periodicals archive ?
In essence, the sarcoplasmic reticulum removes calcium from the inner fluid more slowly in older hearts because there are fewer pumps, and those that remain don't work as well because of communication breakdowns between the brain and the heart.
If these pumps aren't working properly or have shut down, the sarcoplasmic reticulum won't fill as well as it should with calcium, and there won't be enough calcium to fulfill the heart cells' needs, particularly during exercise or stress.
The current study aims to shed some light on the effect of Chinese traditional medicine on essential hypertension in human patients by analyzing changes in spontaneously hypertensive rats (SHR) after treatment with Pra-c, including early changes of sarcoplasmic reticulum phospholamban gene expression in myocardium, to achieve cellular calcium homeostasis and improve cardiac systolic and diastolic function.
Additionally, alterations in sarcolemmal and sarcoplasmic reticulum membranes are evident.
The Sarcoplasmic Reticulum Ca2+ Pump: Inhibition by Thapsigargin and Enhancement by Adenovirus-mediated Gene Transfer.
Kinetic studies of calcium-induced calcium release in cardiac sarcoplasmic reticulum vesicles.
Influence of thyroid hormone and retinoic acid on slow sarcoplasmic reticulum Ca+ ATPase and myosin heavy chain gene expression in cardiac myosites.
Oxidative stress impairs the function of the sarcoplasmic reticulum by oxidation of sulfhydryl groups in the [Ca.
In recentyears, some authors used a genetic strategy to modify cellular calcium handling by overexpressing sarcoplasmic reticulum ATPase via an adenovirus vector similar to pharmacologic strategies for reducing cytosolic free calcium, such as calcium channel blockers and beta-blockers (10).
Celladon is developing both biologics and small molecules targeting a key enzyme deficiency in advanced heart failure, the sarcoplasmic reticulum calcium pump (SERCA2a), which promote contractility but without the negative consequences of current inotropic therapies.
2+] pumps of the sarcoplasmic reticulum or endoplasmic reticulum (SERCA) plays an important role in vessel tone.