saquinavir /sa·quin·a·vir/ (sah-kwin´ah-vir) an HIV protease inhibitor that causes formation of immature, noninfectious viral particles; used as the base or the mesylate salt in treatment of HIV infection and AIDS.
saquinavir,
sa·quin·a·vir (s -kw n -vîr)n. A protease-inhibiting drug usually used in combination with other drugs to suppress the replication of HIV. |
saquinavir,
an antiviral.
indications It is used to treat HIV in combination with zidovudine and zalcitabine.
contraindication Known hypersensitivity to this drug prohibits its use.
adverse effects Adverse effects of this drug include buccal mucosa ulceration, headache, musculoskeletal pain, asthenia, and hyperglycemia. Common side effects are diarrhea, abdominal pain, nausea, paresthesia, and rash.
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