sandwich immunoassay


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sandwich immunoassay

An immunoassay in which the analyte is bound to a solid phase and a labeled reagent subsequently bound immunochemically to the analyte.
See also: immunoassay
References in periodicals archive ?
Optimal scheme of assay using competitive or sandwich immunoassays of rabbit IgG was used.
We focused on the antimetatype antibody--based immunoassay because it is the only nonconventional sandwich immunoassay proposed so far that enables simultaneous recognition of a hapten by 2 antibodies, which could be a key advantage to develop analytically sensitive and specific immunoassays.
After all, many different novel assay chemistries, reporters, and chemical reagents have been proposed for improving sandwich immunoassays.
20), US patent US 5,532,137], in a sandwich immunoassay.
The aim of this project was to develop a sandwich immunoassay to reliably measure sGPVI and validate the novel assay in a large group of patients with symptomatic coronary artery disease (CAD).
used miniaturized sandwich immunoassays to evaluate the predictive values of cytokine production patterns in a sepsis time course (47).
with polyclonal antibody against epitope 8-29 (Biomedica Gruppe), and a sandwich immunoassay (Roche) that uses polyclonal antibodies specific to amino acid residues 1-21 and 39-50 (3).
In sandwich immunoassays, endogenous biotin binding to streptavidin sites can block the analyteantibody-biotin complexes from binding and becoming immobilized.
Clinical assays for cardiac troponins are sandwich immunoassays directed to stable portions of cardiac cTnI and cTnT.
The CaptSure technology allows solution-phase delivery of antibody pairs in sandwich immunoassays, thus enabling the simultaneous formation and immobilisation of the analyte immunocomplex in a single assay incubation.