sanctuary site

sanctuary site

[sangk′cho̅o̅·er′ē]
Etymology: L, sanctus, sacred, situs, location
an area of the body that is poorly penetrated by pharmacological agents and therefore is a place in which tumor cells or infectious organisms can escape the effects of drug therapy. For example, because most drugs that are effective against the human immunodeficiency virus (HIV) do not cross the blood-brain barrier, the central nervous system provides an area in which HIV can avoid the effects of antiviral therapy and from which resistant virus can later emerge.

sanctuary site

Oncology A region of the body–eg, CNS, testes–where leukemia cells are relatively protected from the cytolytic effects of systemic chemotherapy. See Remission.
References in periodicals archive ?
By: MENA CAIRO - 17 July 2017: Palestinian Ambassador here and its permanent representative to the Arab League (AL) Gamal al Shobaky warned against the recent Israeli measures in Al Aqsa Mosque, stressing that they aim at dividing this sanctuary site like the Ibrahimi Mosque.
It turned out the eye is another sanctuary site for cancer cells, like the spinal cord.
A coalition of homeless advocates - called Homeless Health Sanctuary Site Council - has agreed to manage the campsite next to the Science Factory.
The second project awarded to WCMC-Q will examine whether activated endothelial cells, which line the interior surface of blood vessels and lymphatic vessels, represent a sanctuary site for ovarian cancer cells, providing resistance to drug treatment and allowing recurrence of the disease.
Sarkar & Bain (2007) analysed habitat relationships in River Gerua at the sanctuary site, and found three grouped fish species occupying distinct habitats.
The assessment team found the youths to be the most knowledgeable and best-informed group of young people they have encountered at any sanctuary site.
Al-Radi, Phlamoudhi Vounari: A Sanctuary Site in Cyprus [Goteborg: Astrom], 1983), much of the material from these excavations remained in storage at Columbia University, unanalyzed and unpublished.
We want to take this opportunity to thank all our supporters - SARA chairman Ann Prosser, left, and how we told of the purchase of the sanctuary site last year, right Picture by TOM BANKS
One, the Sanctuary site, was used to demonstrate the ecosystem benefits of conventional vs.
Hence the brain remains a sanctuary site for metastatic disease, explained Dr.
FOXRUSH FARM: Members of SARA toast the proposed new sanctuary site Picture by Peter Reimann
The search is still on for a sanctuary site of at least five acres, with buildings which can be developed.