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sanctuary site |
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sanctuary site [sangk′cho̅o̅·er′ē] Etymology: L, sanctus, sacred, situs, location an area of the body that is poorly penetrated by pharmacologic agents and therefore is a place in which tumor cells or infectious organisms can escape the effects of drug therapy. For example, because most drugs that are effective against the human immunodeficiency virus (HIV) do not cross the blood-brain barrier, the central nervous system provides an area in which HIV can avoid the effects of antiviral therapy and from which resistant virus can later emerge. sanctuary site Oncology A region of the body–eg, CNS, testes–where leukemia cells are relatively protected from the cytolytic effects of systemic chemotherapy. See Remission. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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