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salicylism

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salicylism /sal·i·cyl·ism/ (sal´ĭ-sil″izm) toxic effects of overdosage with salicylic acid or its salts, usually marked by tinnitus, nausea, and vomiting.
sal·i·cyl·ism (sl-s-lzm)
n.
A toxic syndrome caused by excessive doses of salicylic acid or any of the salicylates.

salicylism
[sal′isil′izəm]
Etymology: Gk, salix, willow, hyle, matter, ismos, practice
a syndrome of salicylate toxicity. See also salicylate poisoning.

salicylism (sal´isil´izm),
n a toxic state resulting from excess ingestion of salicylates.

salicylism
toxic signs caused by salicylic acid.

salicylism
Toxicology Acute Sx due to aspirin–salicylate overdose, causing a severe metabolic acidosis and a large anion gap; early, salicylates stimulate respiration by central mechanisms–↓ PaCO2 and plasma bicarbonate levels; salicylates interfere with mitochondrial metabolism; when mitochondria degenerate, there is a release of unmeasured organic acids, and ↑ anion gap Clinical Severe headache, N&V, ringing in ears, confusion, ↑ pulse, ↑ respiratory rate. See Salicylates.


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