infantile spasm

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in·fan·tile spasm

brief (1-3 second) muscular spasms in infants with West syndrome, which often appear as nodding or salaam spasms.
Synonym(s): salaam convulsions
An early onset condition characterised by a triad:
(1) Infantile spasms,
(2) Interictal EEG pattern termed hypsarrhythmia, and
(3) Mental retardation. Per the international classification, the diagnosis can be made in the presence of two of the three symptoms. The frequent onset of West syndrome in infancy suggests that CNS immaturity may play a key role in its pathogenesis. The clinical response to ACTH and glucocorticoids may be linked to suppression of corticotropin-releasing hormone production

infantile spasm

Seizure marked by momentary flexion or extension of the neck, trunk, extremities, or any combination, with onset occurring in the first year of life. Although infantile spasms subside in late infancy, many affected children develop other types of seizures and may be severely retarded.
See also: spasm