saccharopine


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sac·cha·ro·pine

(sak'ă-rō-pēn'),
A derivative of α-ketoglutarate and l-lysine that is an intermediate in l-lysine catabolism; elevated in cases of saccharopinuria.

saccharopine

/sac·cha·ro·pine/ (sak´ah-ro-pēn) an intermediate in the metabolism of lysine, accumulating abnormally in some disorders of lysine degradation.
References in periodicals archive ?
Although CDSs involved in intermediary metabolism were underrepresented among the deleted genes, 21 (42%) of deleted CDSs of this category were dehydrogenases (such as acyl-CoA short-chain alcohol, saccharopine, and aldehyde dehydrogenases), which are central enzymes in anaerobic metabolism (22) and important for survival in poorly oxygenated environments such as soil (23).
The major pathway for L-Lys metabolism in the liver occurs through the intermediate saccharopine (Hutzler and Dancis, 1968).
The major pathway of L-Lys metabolism in animals occurs through the intermediate saccharopine.