Among the topics are inheritance patterns, ethical issues, primary congenital glaucoma and juvenile open angle glaucoma, Margan syndrome and other causes of ectopic lentis, familial exudative vitreoretinopathy, retinitis pigmentosa, cone-rod dystrophy, enhanced S-cone
syndrome and other NR2ES-related retinal dystrophies, congenital stationary night blindness, optic nerve hypoplasia, and Leber hereditary optic neuropathy.
Cortical OFF-potentials from the S-cone
pathway reveal neural damage in early glaucoma.
Studies in the literature concerning BCD have reported pathologic ERG responses at non-detectable levels, (1,12,13) a- and b-wave amplitude attenuation on scotopic strong flash ERG, (14) reduced rod b-wave amplitude, (1,15) attenuated a- and b-wave amplitudes on photopic ERG, (15,16) decreased 30-Hz flicker amplitude, (1,16) and abnormal S-cone ERG findings.
Nondetectable S-cone electroretinogram in a patient with crystalline retinopathy.
The blue and yellow color deficiency is called tritanomaly and affects the S-cone
, creating a blue-yellow weakness.
Washington, Sept 2 (ANI): A new study has provided insight into the molecular basis of a rare retinal degenerative disease called Enhanced S-Cone Syndrome, also known as Goldman-Favre Syndrome.
Lead researcher Debarshi Mustafi, who is earning his medical degree and PhD in pharmacology at Case Western Reserve, and his team found that when the natural renewal process fails, metabolites are locked in, build up and turn toxic, killing cells over time in Enhanced S-Cone Syndrome.
Professor Leo Peichl of Germany's Max Planck Institute considered that because the spectral composition of light in clear ocean waters increasingly becomes blue with depth, S-cone loss would seem particularly disadvantageous.
While humans have three colour cones in their retinae (red, green and blue), most terrestrial mammals have two cones: long-to-middle-wave-sensitive L-cones that are commonly green, and short-wave-sensitive S-cones -- commonly blue.
24) A loss in the sensitivity of the S-cone pathway in patients with diabetic retinopathy has been demonstrated with psychophysical (5) and electrophysiological techniques.
A significant correlation between the loss in the S-cone pathway sensitivity and degree of retinopathy has also been found.
18-20,23,24) In the central 2[degrees] of vision, the S-cone
photopigment density is thought to be 5-20% lower than that of the L- and M-cones.