royal malady

var·ie·gate por·phyr·i·a (VP),

[MIM*176200]
porphyria characterized by abdominal pain and neuropsychiatric abnormalities, by dermal sensitivity to light and mechanical trauma, by increased fecal excretion of proto- and coproporphyrin, and by increased urinary excretion of δ-aminolevulinic acid, porphobilinogen, and porphyrins; due to a deficiency of protoporphyrinogen oxidase; autosomal dominant inheritance, caused by mutation in the gene for protoporphyrinogen oxidase (PPOX) on chromosome 1q.

royal malady

(1) Variegate porphyria, see there. 
(2) Factor VIII deficiency, see there.
References in periodicals archive ?
History of the Royal Malady (1789), an expose of George III's household and the rumored marriage of the Prince of Wales to a Roman Catholic divorcee named Mrs.
The loyal, if conflicted, narrator of Royal Malady manages to supply these needs in a way meant to justify both his and his readers' motives: "A curiosity that in the common events of life is criminal, loses its name on this occasion, and ought to be termed laudable anxiety and ardent affection" (Withers 11).
If Philip Withers impersonates a court page in History of the Royal Malady, in other exposes aimed at the Prince of Wales and Mrs.
Like Royal Malady, Godwin's novel features a servant-narrator caught between traditional loyalties and a curiosity by turns reprehensible and civic-minded.

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