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(klok) a device for measuring time.
biological clock  the physiologic mechanism which governs the rhythmic occurrence of certain biochemical, physiologic, and behavioral phenomena in living organisms.


1. An instrument other than a watch for measuring or indicating time, especially a mechanical or electronic device having a numbered dial and moving hands or a digital display.
2. A biological clock.
v. clocked, clocking, clocks
To register or record with a mechanical device: clocked the winds at 60 miles per hour.

clock′er n.


A gene on chromosome 4q12 that encodes a ubiquitously expressed human homolog of the mouse clock gene, which forms a heterodimer with ARNTL and activates E-box element transcription of several circadian clock proteins (e.g., PER1 and PER2). CLOCK is highly expressed in the suprachiasmatic nucleus.

Molecular pathology
CLOCK-ARNTL double mutations in the PAS domains result in syngernistic desensitisation to high levels of CRY on repression of CLOCK-ARNTL transcriptional activity of PER1, disrupting circadian rhythmicity.


A device for measuring time.

biological clock

1. An internal system in organisms that influences behavior in a rhythmic manner. Functions such as growth, feeding, secretion of hormones, the rate of drug action, the wake-sleep cycle, the menstrual cycle, and reproduction coincide with certain external events such as day and night, the tides, and the seasons. Biological clocks appear to be set by environmental conditions in some animals, but if these animals are isolated from their environment they continue to function according to the usual rhythm. A gradual change in environment does produce a gradual change in the timing of the biological clock. See: circadian; maladaptation to night work; zeitgeber
2. A colloquial term for the decrease in fertility that accompanies aging, particularly as women approach the age of 35.

Patient discussion about clock

Q. How do you wake up in the morning if your narcolepsy is so severe you can't hear the alarm clock, phone ring? biggest problem is sleep paralysis, can't wake up. Late for work, everything, life is suffering because of severity. Have tried ritalin, natural supplements, hypnosis therapy, Provigal, antidepressants, nothing seems to work. Employer thinks it's an excuse, friends are irritated, I'm at my wits end. Life is spent sleeping more than awake.

A. Narcolepsy cannot yet be cured. But EDS and cataplexy, the most disabling symptoms of the disorder, can be controlled in most patients with drug treatment. Often the treatment regimen is modified as symptoms change. For decades, doctors have used central nervous system stimulants-amphetamines such as methylphenidate, dextroamphetamine, methamphetamine, and pemoline-to alleviate EDS and reduce the incidence of sleep attacks. For most patients these medications are generally quite effective at reducing daytime drowsiness and improving levels of alertness. However, they are associated with a wide array of undesirable side effects so their use must be carefully monitored. Common side effects include irritability and nervousness, shakiness, disturbances in heart rhythm, stomach upset, nighttime sleep disruption, and anorexia. For full article: Hope this helps.

More discussions about clock
References in periodicals archive ?
In Al Attiya market and its surroundings in the Industrial Area many supermarkets and groceries are now open round the clock.
However, outlets like cafes will have to pay extra charges for their licence if they want to keep open round the clock.
If supermarkets are to sell alcohol round the clock they need to step up to the challenge of responsible practice, and that means a commitment not to run irresponsible cheap drink promotions that encourage people to drink too much, and no sales to people who are underage or obviously drunk.
Control room has also been set up for round the clock monitoring of ijtima, he added.
The immigration office at terminal-3 of the Dubai International Airport will remain open round the clock during the Eid Al Fitr holiday.
They work in three shifts round the clock to provide patients with quality service.
As with all Jackpotjoy bingo, Round the Clock is stuffed full of exciting bonus games, each offering new ways to win more cash.
CELEBRITY survivor fans will be able to watch the new series of the show round the clock, producers revealed yesterday.
BUILDERS are working round the clock in a desperate bid to finish the pounds 32million Museum of Scotland so the Queen can open it on Monday.
The software that Bentley has already begun will enable barter exchanges, and the companies that barter through them, access round the clock to a user-friendly, online trade exchange -- tailored to their needs.
Tenders are invited for Round the clock security upkeep maintenance of Running Room including lawn & Garden in Running Room premises Cooking & Serving of food including subsidized meals to occupants of Running Room (RR) Round the clock serving of Train ordering calls to occupants of RR Collection of soiled linens from RR and delivering back duly washed & ironed linens providing washed linens to occupants at Running room of BALAMAU for a period of 3 years.
KARACHI -- Administrator, Karachi Metropolitan Corporation, Saqib Ahmed Soomro has sought ready availability of all relevant gadgets and medicines besides round the clock presence of doctors and para-medical staff to handle any untoward situation in the metropolis.