round cell sarcoma

round cell sar·co·ma

obsolete term for an undifferentiated malignant neoplasm, believed to be of mesenchymal origin, composed chiefly of closely packed round cells.

round cell sarcoma

(1) A sarcoma (malignant tumour of mesenchymal origin) composed of round cells—e.g., epithelioid sarcoma, biphasic synovial sarcomas, some PEComas. The term is based on its histologic appearance and was used early in the diagnostic workup, before the results of immunohistochemical stains allow it to be slotted into a more specific category.
(2) An obsolete term for a lymphoma with round cells (lymphocytes) and a sarcomatoid stroma.
(3) Round cell tumour, see there. 
(4) Ewing sarcoma, see there.
References in periodicals archive ?
Hence a diagnosis of malignant round cell sarcoma was made.
1 The malignant tumors in children include round cell sarcomas (Primitive Neu- roectodermal Tumors and Rhabdomyosarcomas), Hodgkin / Non-Hodgkin Lymphomas, Alveolar soft part sarcoma and fibrosarcomas.
Chloe Bigmore, of Laleston, near Bridgend, died aged 14 in 2007 after contracting a rare cancer called desmoplastic round cell sarcoma.
High-grade round cell sarcoma, NOS 1/17 (6) 0/5 (0) Spindle cell sarcomas (n = 40) Monophasic synovial sarcoma .
There were 5 major morphologic patterns that emerged in which FISH was used including high-grade round cell sarcomas, spindle cell sarcomas, low-grade myxoid neoplasms, adipocytic neoplasms, and melanocytic neoplasms without an epidermal component.
FISH, not surprisingly, was most commonly used in the evaluation of high-grade round cell sarcomas (n = 67).
A small subset of round cell sarcomas clinically and histologically mimic Ewing sarcoma but fail to demonstrate any of the reported cytogenetic abnormalities described above.
High prevalence of CIC fusion with double-homeobox (DUX4) transcription factors in EWSR1-negative undifferentiated small blue round cell sarcomas.
In the present series, round cell sarcomas were more commonly found on lower extremities, which is comparable to that found by Roy et al.
Undifferentiated small round cell sarcomas with rare EWS gene fusions: identification of a novel EWS-SP3 fusion and of additional cases with the EWS-ETV1 and EWS-FEV fusions.
The histologic and immunohistochemical similarities, ranging from benign conditions such as osteomyelitis to monotonous round cell sarcomas, should be borne in mind when assessing these neoplasms to avoid misdiagnosis and inappropriate treatment.