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rough endoplasmic reticulum

   Also found in: Acronyms 0.01 sec.
rough endoplasmic reticulum
parts of the endoplasmic reticulum to which ribosomes are attached on the cytoplasmic side; involved in the biosynthesis of proteins for export to the outside of the cell and enzymes to be incorporated into cellular organelles such as lysosomes. See also endoplasmic reticulum.


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The features consistent with myofibroblastic origin include actin positivity by immunohistochemistry and the presence of rough endoplasmic reticulum and intracytoplasmic densities of smooth muscle myofilaments by electron miscroscopy.
Their cytoplasm is rich in ribosomes, vesicles, vacuoles containing electron-dense material and large mitochondria; but the rough endoplasmic reticulum and Golgi complexes are sparse.
 
 
 
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