rotaviruses


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rotaviruses

Enteroviridae viruses that are the leading recognized cause of diarrhoea-related illness and death in infants and young children. A live attenuated vaccine is available and provides excellent protection against severe rotavirus gastroenteritis. A pentavalent human-bovine reassortant rotavirus vaccine is also available. This protects against the four most prevalent human strains. The name of the virus derives from the wheel-like appearance on electron microscopy.
References in periodicals archive ?
After phylogenetic analysis of the concatenated genome (Figure 2) and individual genome segments (online Technical Appendix Figure 3), fox-288356 grouped with avian group A rotaviruses.
In the present study, we aimed to determine the prevalence and the genotype distribution of rotaviruses in children admitted to Rize Training and Research Hospital in Eastern Black Sea region of Turkey.
Unsuccessful attempts to reduce rotavirus infection with this treatment led scientists to group rotaviruses into two classes: 'sialidase-sensitive' and 'sialidase-insensitive' strains," said von Itzstein.
Rotaviruses are classified by a scheme of groups and multiple serotypes/genotypes within each group.
Rotaviruses cause the majority of diarrhea cases in infants and children.
New research has found a link between rotaviruses and type 1 diabetes, which usually starts in childhood and affects 20,000 youngsters under 18-years-old in the UK.
Because rotaviruses were P- and G-typed by PCR using VP4- and VP7-specific primers, we further confirmed the presence of rotavirus in samples from nonsecretor patients.
Globally, rotaviruses account for approximately 138 million cases of infantile gastroenteritis each year and it was recently reported that rotavirus is responsible for approximately 440,000 deaths per year, a child a minute, the majority of which occur in the Indian subcontinent, sub-Saharan Africa and South America.
Most rotaviruses circulating in the United States belong to a limited number of strains, routinely characterized by serologic or genetic identification of the outer capsid protein antigens viral protein (VP) 7, which defines G types, and VP4, which defines P types (6,7).
Rotaviruses occur widely among humans and many animal species throughout the world, and are important causes of gastroenteritis.
Rotaviruses, members of the Reoviridae family, are the single most important aetiological agents of severe diarrhoea in infants and young children worldwide (1-3).